SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2crq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		3 / 3 SER A  59
GLU A  62
GLU A  61
 None
 0.71A 1eqbD-2crqA:
undetectable		 1eqbD-2crqA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		3 / 3 SER A  59
GLU A  62
GLU A  61
 None
 0.71A 1eqbB-2crqA:
undetectable		 1eqbB-2crqA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		5 / 12 ILE A  87
GLY A  90
THR A  91
GLU A  60
THR A  63
 None
 1.48A 3r75A-2crqA:
undetectable		 3r75A-2crqA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		5 / 12 ILE A  87
GLY A  90
THR A  91
GLU A  60
THR A  63
 None
 1.49A 3r75B-2crqA:
undetectable		 3r75B-2crqA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		5 / 11 ILE A  87
GLY A  90
THR A  91
GLU A  60
THR A  63
 None
 1.46A 3r76A-2crqA:
undetectable		 3r76A-2crqA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		5 / 11 ILE A  87
GLY A  90
THR A  91
GLU A  60
THR A  63
 None
 1.47A 3r76B-2crqA:
undetectable		 3r76B-2crqA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		4 / 7 SER A  22
GLU A  65
ILE A  66
ASN A  23
 None
 0.99A 4d39B-2crqA:
undetectable		 4d39B-2crqA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 2crq MITOCHONDRIAL
TRANSLATIONAL
INITIATION FACTOR 3
(Mus
musculus) 		5 / 12 ILE A  66
ILE A  50
VAL A  48
VAL A  46
PHE A  97
 None
 1.04A 4y0pA-2crqA:
undetectable		 4y0pA-2crqA:
18.56