SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cs3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_B_CUB4_0
(BETA-CARBONIC
ANHYDRASE)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		4 / 6 CYH A  67
CYH A  33
PRO A  34
SER A  35
 ZN  A 400 (-2.3A)
ZN  A 400 (-2.3A)
None
ZN  A 400 ( 4.7A)
 0.98A 1ekjA-2cs3A:
undetectable
1ekjB-2cs3A:
undetectable		 1ekjA-2cs3A:
17.70
1ekjB-2cs3A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		4 / 6 LYS A  51
LEU A  87
ALA A  55
THR A  56
 None
 1.07A 1ictB-2cs3A:
undetectable		 1ictB-2cs3A:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		4 / 8 VAL A  59
PRO A  62
VAL A  31
GLU A  82
 None
 0.93A 1jtvA-2cs3A:
undetectable		 1jtvA-2cs3A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		4 / 5 PHE A  41
ILE A  20
GLY A  64
HIS A  39
 None
ZN  A 200 ( 4.5A)
None
ZN  A 400 (-3.1A)
 1.39A 3r0lD-2cs3A:
undetectable		 3r0lD-2cs3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		3 / 3 PHE A  41
CYH A  33
HIS A  39
 None
ZN  A 400 (-2.3A)
ZN  A 400 (-3.1A)
 1.04A 3u9fF-2cs3A:
undetectable		 3u9fF-2cs3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		3 / 3 PHE A  41
CYH A  33
HIS A  39
 None
ZN  A 400 (-2.3A)
ZN  A 400 (-3.1A)
 1.04A 3u9fG-2cs3A:
undetectable		 3u9fG-2cs3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		3 / 3 PHE A  41
CYH A  33
HIS A  39
 None
ZN  A 400 (-2.3A)
ZN  A 400 (-3.1A)
 0.98A 3u9fL-2cs3A:
undetectable		 3u9fL-2cs3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		3 / 3 PHE A  41
CYH A  61
HIS A  39
 None
ZN  A 400 (-2.3A)
ZN  A 400 (-3.1A)
 1.30A 3u9fL-2cs3A:
undetectable		 3u9fL-2cs3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		3 / 3 PHE A  41
CYH A  33
HIS A  39
 None
ZN  A 400 (-2.3A)
ZN  A 400 (-3.1A)
 0.99A 3u9fS-2cs3A:
undetectable		 3u9fS-2cs3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 2cs3 PROTEIN C14ORF4
(Homo
sapiens) 		4 / 6 LYS A  51
LEU A  87
ALA A  55
THR A  56
 None
 1.06A 4i89A-2cs3A:
undetectable		 4i89A-2cs3A:
25.81