SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cs4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 2cs4 PROTEIN C12ORF2
(Homo
sapiens) 		4 / 7 ALA A  38
GLY A  42
LEU A  84
ARG A  85
 None
 0.85A 2uyqA-2cs4A:
undetectable		 2uyqA-2cs4A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 2cs4 PROTEIN C12ORF2
(Homo
sapiens) 		5 / 9 LEU A  82
ASP A  15
ILE A  41
ILE A  35
LEU A  10
 None
 1.10A 3u7sA-2cs4A:
undetectable		 3u7sA-2cs4A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2cs4 PROTEIN C12ORF2
(Homo
sapiens) 		4 / 8 GLU A  57
VAL A  80
LEU A  60
THR A  48
 None
 0.98A 5sxqA-2cs4A:
undetectable		 5sxqA-2cs4A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 2cs4 PROTEIN C12ORF2
(Homo
sapiens) 		4 / 8 GLU A  57
VAL A  80
LEU A  60
THR A  48
 None
 0.95A 5sxtA-2cs4A:
undetectable		 5sxtA-2cs4A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2cs4 PROTEIN C12ORF2
(Homo
sapiens) 		4 / 8 GLU A  57
VAL A  80
LEU A  60
THR A  48
 None
 0.92A 5sxtB-2cs4A:
undetectable		 5sxtB-2cs4A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 2cs4 PROTEIN C12ORF2
(Homo
sapiens) 		4 / 8 GLU A  57
VAL A  80
LEU A  60
THR A  48
 None
 0.96A 5syjB-2cs4A:
undetectable		 5syjB-2cs4A:
8.73