SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cs7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.45A 1rjoA-2cs7A:
undetectable		 1rjoA-2cs7A:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.34A 1rkyA-2cs7A:
undetectable		 1rkyA-2cs7A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.72A 1v54A-2cs7A:
undetectable		 1v54A-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.73A 1v54N-2cs7A:
undetectable		 1v54N-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.72A 1v55A-2cs7A:
undetectable		 1v55A-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.73A 1v55N-2cs7A:
undetectable		 1v55N-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.51A 1w2zA-2cs7A:
undetectable		 1w2zA-2cs7A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.45A 1w2zB-2cs7A:
undetectable		 1w2zB-2cs7A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.47A 1w2zC-2cs7A:
undetectable		 1w2zC-2cs7A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.42A 1w2zD-2cs7A:
undetectable		 1w2zD-2cs7A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 ILE A  16
HIS A  33
GLY A  21
LEU A  40
TYR A   3
 None
ZN  A 201 (-3.2A)
None
None
None
 1.23A 2azyA-2cs7A:
undetectable		 2azyA-2cs7A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 THR A  20
PRO A  36
TYR A  34
 None
 0.98A 2dxrA-2cs7A:
undetectable		 2dxrA-2cs7A:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.71A 2dyrA-2cs7A:
undetectable		 2dyrA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.73A 2dyrN-2cs7A:
undetectable		 2dyrN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.72A 2dysA-2cs7A:
undetectable		 2dysA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.75A 2dysN-2cs7A:
undetectable		 2dysN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.70A 2eijA-2cs7A:
undetectable		 2eijA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.73A 2eijN-2cs7A:
undetectable		 2eijN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.70A 2eikA-2cs7A:
undetectable		 2eikA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.75A 2eikN-2cs7A:
undetectable		 2eikN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.71A 2eilA-2cs7A:
undetectable		 2eilA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.76A 2eilN-2cs7A:
undetectable		 2eilN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.75A 2eimA-2cs7A:
undetectable		 2eimA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.74A 2eimN-2cs7A:
undetectable		 2eimN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.72A 2einA-2cs7A:
undetectable		 2einA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.48A 2oqeA-2cs7A:
undetectable		 2oqeA-2cs7A:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.49A 2oqeB-2cs7A:
undetectable		 2oqeB-2cs7A:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.46A 2oqeC-2cs7A:
undetectable		 2oqeC-2cs7A:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.47A 2oqeD-2cs7A:
undetectable		 2oqeD-2cs7A:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.48A 2oqeF-2cs7A:
undetectable		 2oqeF-2cs7A:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.39A 2w0qA-2cs7A:
undetectable		 2w0qA-2cs7A:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.43A 2w0qB-2cs7A:
undetectable		 2w0qB-2cs7A:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.75A 3abkA-2cs7A:
undetectable		 3abkA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.74A 3ag2A-2cs7A:
undetectable		 3ag2A-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.76A 3ag3A-2cs7A:
undetectable		 3ag3A-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.71A 3ag4A-2cs7A:
undetectable		 3ag4A-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.74A 3ag4N-2cs7A:
undetectable		 3ag4N-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.46A 3hiiA-2cs7A:
undetectable		 3hiiA-2cs7A:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  31
HIS A  33
HIS A  28
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.1A)
 0.44A 3hiiB-2cs7A:
undetectable		 3hiiB-2cs7A:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.75A 3x2qA-2cs7A:
undetectable		 3x2qA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.77A 5b1aN-2cs7A:
undetectable		 5b1aN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.72A 5b1bA-2cs7A:
undetectable		 5b1bA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.73A 5b1bN-2cs7A:
undetectable		 5b1bN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.71A 5b3sA-2cs7A:
undetectable		 5b3sA-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.72A 5b3sN-2cs7A:
undetectable		 5b3sN-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.74A 5iy5A-2cs7A:
undetectable		 5iy5A-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.74A 5iy5N-2cs7A:
undetectable		 5iy5N-2cs7A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cs7 PNEUMOCOCCAL
HISTIDINE TRIAD A
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 HIS A  28
HIS A  31
HIS A  33
 ZN  A 201 (-3.1A)
ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
 0.73A 5x19A-2cs7A:
undetectable		 5x19A-2cs7A:
7.24