SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2csg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 4 LEU A 266
VAL A 359
ILE A 188
TRP A 102
 None
 1.49A 1s9qB-2csgA:
undetectable		 1s9qB-2csgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 ALA A 365
TYR A 184
ILE A 182
ASP A 390
 None
 1.19A 1upfA-2csgA:
undetectable		 1upfA-2csgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 ALA A 365
TYR A 184
ILE A 182
ASP A 390
 None
 1.17A 1upfC-2csgA:
undetectable		 1upfC-2csgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 11 ILE A  74
ALA A  70
PHE A 161
SER A 336
ILE A  64
 None
 1.26A 2blaA-2csgA:
undetectable		 2blaA-2csgA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 TRP A 212
VAL A 279
ARG A  85
 None
 0.94A 3b0wA-2csgA:
undetectable		 3b0wA-2csgA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 TYR A 184
ALA A 381
ALA A 373
MET A 367
 None
 1.28A 3d91A-2csgA:
undetectable		 3d91A-2csgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 GLY A 274
GLY A 272
GLU A 136
ALA A 348
 None
 0.66A 3fpjB-2csgA:
undetectable		 3fpjB-2csgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 LYS A  91
ILE A 328
ASP A 268
GLU A 332
 None
 0.88A 3kp6A-2csgA:
0.0
3kp6B-2csgA:
undetectable		 3kp6A-2csgA:
14.22
3kp6B-2csgA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 HIS A 340
VAL A 343
VAL A  82
ALA A  88
 None
 1.03A 3kp6B-2csgA:
undetectable		 3kp6B-2csgA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE A 257
HIS A 239
THR A 241
VAL A 243
 None
 0.76A 3lb3A-2csgA:
undetectable		 3lb3A-2csgA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE A 257
HIS A 239
THR A 241
VAL A 243
 None
 1.03A 3lb3B-2csgA:
undetectable		 3lb3B-2csgA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 8 GLN A 219
GLN A 218
LEU A 213
LEU A 302
 None
 0.83A 3ozwA-2csgA:
undetectable		 3ozwA-2csgA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 ARG A 187
PHE A 391
PRO A 388
 ICT  A 501 (-3.6A)
ICT  A 501 (-4.5A)
None
 0.87A 3zoaB-2csgA:
undetectable		 3zoaB-2csgA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 ASN A 113
TRP A 400
ASP A 108
 None
 1.27A 4a7tA-2csgA:
undetectable
4a7tF-2csgA:
undetectable		 4a7tA-2csgA:
20.21
4a7tF-2csgA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 ASP A 186
ARG A 187
TYR A 361
 ICT  A 501 (-2.6A)
ICT  A 501 (-3.6A)
SIN  A 502 (-4.2A)
 0.58A 5a7mA-2csgA:
undetectable		 5a7mA-2csgA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 ASP A 186
ARG A 187
TYR A 361
 ICT  A 501 (-2.6A)
ICT  A 501 (-3.6A)
SIN  A 502 (-4.2A)
 0.61A 5a7mB-2csgA:
undetectable		 5a7mB-2csgA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 ASN A 371
PRO A 366
GLN A 159
 None
 0.90A 6jnhA-2csgA:
undetectable		 6jnhA-2csgA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2csg PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 ASN A 371
PRO A 366
GLN A 159
 None
 0.91A 6jogA-2csgA:
undetectable		 6jogA-2csgA:
17.18