SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ctm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 12 HIS A  28
PHE A  52
ILE A  50
GLU A  83
LEU A  80
 None
 1.42A 4r88A-2ctmA:
undetectable		 4r88A-2ctmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 12 HIS A  28
PHE A  52
ILE A  50
GLU A  83
LEU A  80
 None
 1.44A 4r88B-2ctmA:
undetectable		 4r88B-2ctmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 12 HIS A  28
PHE A  52
ILE A  50
GLU A  83
LEU A  80
 None
 1.43A 4r88C-2ctmA:
undetectable		 4r88C-2ctmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 12 HIS A  28
PHE A  52
ILE A  50
GLU A  83
LEU A  80
 None
 1.42A 4r88D-2ctmA:
undetectable		 4r88D-2ctmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 12 HIS A  28
PHE A  52
ILE A  50
GLU A  83
LEU A  80
 None
 1.43A 4r88E-2ctmA:
undetectable		 4r88E-2ctmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 12 HIS A  28
PHE A  52
ILE A  50
GLU A  83
LEU A  80
 None
 1.42A 4r88F-2ctmA:
undetectable		 4r88F-2ctmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 12 LEU A  82
HIS A  78
ILE A  31
ALA A  38
ILE A  50
 None
 0.99A 4rp8C-2ctmA:
undetectable		 4rp8C-2ctmA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2ctm VIGILIN
(Homo
sapiens) 		5 / 10 ALA A  29
LYS A  41
ILE A  42
ILE A  79
VAL A  63
 None
 1.21A 5nukA-2ctmA:
undetectable		 5nukA-2ctmA:
19.57