SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ctr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 9 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 1.02A 1gtfD-2ctrA:
undetectable
1gtfE-2ctrA:
undetectable		 1gtfD-2ctrA:
24.71
1gtfE-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 1gtfJ-2ctrA:
undetectable
1gtfK-2ctrA:
undetectable		 1gtfJ-2ctrA:
24.71
1gtfK-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		4 / 7 THR A  77
SER A  78
TYR A  10
LEU A  59
 None
 1.13A 1ibgL-2ctrA:
undetectable		 1ibgL-2ctrA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A   7
ALA A  55
ILE A  12
GLY A  72
THR A  77
 None
 0.99A 1utdE-2ctrA:
undetectable
1utdF-2ctrA:
undetectable		 1utdE-2ctrA:
24.71
1utdF-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A   7
ALA A  55
ILE A  12
GLY A  72
THR A  77
 None
 1.01A 1utdH-2ctrA:
undetectable
1utdI-2ctrA:
undetectable		 1utdH-2ctrA:
24.71
1utdI-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5eevA-2ctrA:
undetectable
5eevB-2ctrA:
undetectable		 5eevA-2ctrA:
24.71
5eevB-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5eewA-2ctrA:
undetectable
5eewB-2ctrA:
undetectable		 5eewA-2ctrA:
24.71
5eewB-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5eexA-2ctrA:
undetectable
5eexB-2ctrA:
undetectable		 5eexA-2ctrA:
24.71
5eexB-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5eeyA-2ctrA:
undetectable
5eeyB-2ctrA:
undetectable		 5eeyA-2ctrA:
24.71
5eeyB-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5eezA-2ctrA:
undetectable
5eezB-2ctrA:
undetectable		 5eezA-2ctrA:
24.71
5eezB-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5ef0A-2ctrA:
undetectable
5ef0B-2ctrA:
undetectable		 5ef0A-2ctrA:
24.71
5ef0B-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5ef1A-2ctrA:
undetectable
5ef1B-2ctrA:
undetectable		 5ef1A-2ctrA:
24.71
5ef1B-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5ef2A-2ctrA:
undetectable
5ef2B-2ctrA:
undetectable		 5ef2A-2ctrA:
24.71
5ef2B-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		5 / 10 GLY A  72
THR A  77
GLY A   7
ALA A  55
ILE A  12
 None
 0.99A 5ef3A-2ctrA:
undetectable
5ef3B-2ctrA:
undetectable		 5ef3A-2ctrA:
24.71
5ef3B-2ctrA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 2ctr DNAJ HOMOLOG
SUBFAMILY B MEMBER 9
(Homo
sapiens) 		4 / 5 TYR A  10
LEU A  71
GLY A  72
PHE A  76
 None
 0.90A 5kmdC-2ctrA:
2.1
5kmdD-2ctrA:
3.2		 5kmdC-2ctrA:
13.50
5kmdD-2ctrA:
13.50