SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2cu9 HISTONE CHAPERONE
CIA1
(Schizosaccharomy
ces
pombe) 		4 / 7 ILE A  69
GLY A  68
PHE A  28
ASN A   5
 None
 0.86A 1oniG-2cu9A:
undetectable
1oniI-2cu9A:
undetectable		 1oniG-2cu9A:
20.86
1oniI-2cu9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 2cu9 HISTONE CHAPERONE
CIA1
(Schizosaccharomy
ces
pombe) 		5 / 12 PHE A  24
TRP A  40
ILE A   6
VAL A 114
ILE A  96
 None
 1.32A 1r5lA-2cu9A:
undetectable		 1r5lA-2cu9A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2cu9 HISTONE CHAPERONE
CIA1
(Schizosaccharomy
ces
pombe) 		4 / 7 TYR A  22
VAL A 114
THR A  94
VAL A 141
 None
 0.97A 2qblA-2cu9A:
undetectable		 2qblA-2cu9A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2cu9 HISTONE CHAPERONE
CIA1
(Schizosaccharomy
ces
pombe) 		4 / 8 TYR A  22
VAL A 114
THR A  94
VAL A 141
 None
 0.97A 2qbmA-2cu9A:
undetectable		 2qbmA-2cu9A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 2cu9 HISTONE CHAPERONE
CIA1
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A 140
TRP A 142
SER A 139
 None
 1.20A 5nwwA-2cu9A:
undetectable		 5nwwA-2cu9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2cu9 HISTONE CHAPERONE
CIA1
(Schizosaccharomy
ces
pombe) 		3 / 3 GLU A  75
TYR A  22
ARG A 143
 None
 0.76A 5uunA-2cu9A:
undetectable		 5uunA-2cu9A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2cu9 HISTONE CHAPERONE
CIA1
(Schizosaccharomy
ces
pombe) 		3 / 3 GLU A  75
TYR A  22
ARG A 143
 None
 0.74A 5uunB-2cu9A:
undetectable		 5uunB-2cu9A:
19.00