SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cuh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 2cuh TENASCIN-X
(Homo
sapiens) 		3 / 3 ARG A  80
GLY A  10
PRO A  11
 None
 0.74A 2hreD-2cuhA:
undetectable		 2hreD-2cuhA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 2cuh TENASCIN-X
(Homo
sapiens) 		4 / 7 THR A  12
ALA A  88
PRO A  31
ARG A  77
 None
 0.89A 2ql8A-2cuhA:
undetectable
2ql8B-2cuhA:
undetectable		 2ql8A-2cuhA:
22.22
2ql8B-2cuhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 2cuh TENASCIN-X
(Homo
sapiens) 		3 / 3 PHE A  23
TYR A  61
LEU A  96
 None
 0.72A 3keeB-2cuhA:
undetectable		 3keeB-2cuhA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2cuh TENASCIN-X
(Homo
sapiens) 		3 / 3 PHE A  23
TYR A  61
LEU A  96
 None
 0.60A 3sueB-2cuhA:
undetectable		 3sueB-2cuhA:
23.81