SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		4 / 6 LEU A 130
LEU A 255
LEU A 116
LEU A  67
 None
 0.94A 1errA-2cv6A:
undetectable		 1errA-2cv6A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 9 LEU A 296
ILE A 287
ILE A 284
VAL A 336
ILE A 294
 None
 1.00A 1ohrB-2cv6A:
undetectable		 1ohrB-2cv6A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 9 LEU A 296
ILE A 287
ILE A 284
VAL A 336
ILE A 294
 None
 1.10A 2avoA-2cv6A:
undetectable		 2avoA-2cv6A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		4 / 8 SER A 146
PHE A 144
LEU A  35
LEU A 116
 None
 0.97A 2bfpB-2cv6A:
undetectable		 2bfpB-2cv6A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		4 / 8 SER A 146
PHE A 144
LEU A  35
LEU A 116
 None
 0.95A 2bfpC-2cv6A:
undetectable		 2bfpC-2cv6A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 10 ILE A  99
LEU A 100
VAL A  80
GLY A 103
GLY A  83
 None
 1.25A 2wd9C-2cv6A:
undetectable		 2wd9C-2cv6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		3 / 3 PHE A  16
ASN A  14
PHE A 328
 None
 1.02A 2zbuD-2cv6A:
undetectable		 2zbuD-2cv6A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 9 LEU A 296
ILE A 287
ILE A 284
VAL A 336
ILE A 294
 None
 1.14A 3d1yB-2cv6A:
undetectable		 3d1yB-2cv6A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		3 / 3 ARG A  29
THR A 148
THR A  65
 None
 0.70A 3k2hB-2cv6A:
undetectable		 3k2hB-2cv6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 10 ILE A 108
PHE A 114
ILE A 127
LEU A  67
HIS A  70
 None
 1.19A 3o1cA-2cv6A:
undetectable		 3o1cA-2cv6A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 10 ILE A 108
PHE A 114
ILE A 127
LEU A  67
HIS A  70
 None
 1.16A 3o1xA-2cv6A:
undetectable		 3o1xA-2cv6A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 10 ILE A 108
PHE A 114
ILE A 127
LEU A  67
HIS A  70
 None
 1.14A 3qgzA-2cv6A:
undetectable		 3qgzA-2cv6A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		4 / 8 PHE A  41
TYR A  54
VAL A  56
ILE A 128
 None
 0.94A 4a97G-2cv6A:
undetectable		 4a97G-2cv6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		6 / 12 GLY A 350
ALA A 353
ILE A 282
ASN A 356
ILE A 284
LEU A 258
 None
 1.46A 4azvA-2cv6A:
undetectable		 4azvA-2cv6A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		4 / 7 LEU A  66
THR A 113
THR A  88
VAL A  90
 None
 0.94A 4ik7A-2cv6A:
undetectable		 4ik7A-2cv6A:
16.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 2cv6 SEED STORAGE PROTEIN
(Vigna
radiata) 		5 / 8 HIS A 276
ASN A 278
VAL A 283
LEU A 285
ILE A 330
 None
 0.52A 6cb4A-2cv6A:
46.8		 6cb4A-2cv6A:
50.54