SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 338
MET A 339
PHE A 729
LEU A 393
 None
 1.20A 1ea1A-2cvtA:
undetectable		 1ea1A-2cvtA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 MET A 606
LEU A 512
PHE A 516
LEU A 450
ILE A 695
 None
 1.42A 1hrkB-2cvtA:
undetectable		 1hrkB-2cvtA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 143
VAL A 136
ILE A 135
LEU A 156
 None
 0.84A 1j96A-2cvtA:
2.9		 1j96A-2cvtA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 143
VAL A 136
ILE A 135
LEU A 156
 None
 0.76A 1j96B-2cvtA:
2.7		 1j96B-2cvtA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 470
ALA A 474
MET A 603
LEU A 507
VAL A 509
 None
 1.07A 1s9pA-2cvtA:
undetectable		 1s9pA-2cvtA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 470
ALA A 474
MET A 603
LEU A 507
VAL A 509
 None
 1.08A 1s9pD-2cvtA:
undetectable		 1s9pD-2cvtA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 389
GLY A 722
PRO A 719
THR A 397
 None
 1.14A 2aouB-2cvtA:
2.4		 2aouB-2cvtA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 645
LEU A 649
ILE A 654
LEU A 673
ILE A 670
 None
 1.24A 2f78A-2cvtA:
undetectable		 2f78A-2cvtA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 645
LEU A 649
ILE A 654
LEU A 673
ILE A 670
 None
 1.22A 2f78B-2cvtA:
undetectable		 2f78B-2cvtA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 645
LEU A 649
ILE A 654
LEU A 673
ILE A 670
 None
 1.13A 2f7aA-2cvtA:
undetectable		 2f7aA-2cvtA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 7 THR A 399
ALA A 298
TYR A 300
PHE A 311
 None
 1.16A 2hzqA-2cvtA:
undetectable		 2hzqA-2cvtA:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 SER A 610
THR A 199
VAL A 174
ALA A 208
THR A 210
 None
 1.29A 2nniA-2cvtA:
0.8		 2nniA-2cvtA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 6 SER A 547
ARG A 598
PRO A 556
GLY A 555
 None
 1.40A 2y7pA-2cvtA:
undetectable		 2y7pA-2cvtA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 THR A 602
SER A 543
ALA A 474
ALA A 551
VAL A 597
 None
 1.23A 2yvlC-2cvtA:
undetectable		 2yvlC-2cvtA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 5 THR A 608
THR A 204
HIS A 200
LEU A 481
 None
 1.14A 2zj0A-2cvtA:
undetectable		 2zj0A-2cvtA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 116
SER A 117
PRO A 211
PRO A 213
 None
 1.40A 3bjwC-2cvtA:
undetectable		 3bjwC-2cvtA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 5 THR A 608
THR A 204
HIS A 200
LEU A 481
 None
 1.16A 3ce6A-2cvtA:
undetectable		 3ce6A-2cvtA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 5 THR A 608
THR A 204
HIS A 200
LEU A 481
 None
 1.15A 3ce6C-2cvtA:
undetectable		 3ce6C-2cvtA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 4 THR A 189
VAL A 484
GLY A 209
THR A 210
 None
 1.04A 3cflA-2cvtA:
undetectable		 3cflA-2cvtA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 THR A 204
LEU A 151
GLN A 168
TYR A 155
LEU A 170
 None
 1.42A 3fsuA-2cvtA:
2.4		 3fsuA-2cvtA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 450
TYR A 465
PHE A 467
LEU A 470
 None
 0.97A 3i45A-2cvtA:
2.5		 3i45A-2cvtA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IWM_G_010G6_0
(3C-LIKE PROTEINASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 4 THR A 234
LEU A 250
MET A 275
ASN A 254
 None
 1.21A 3iwmC-2cvtA:
0.0		 3iwmC-2cvtA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 599
ASN A 499
GLU A 433
 None
 0.84A 3kpdC-2cvtA:
undetectable		 3kpdC-2cvtA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 599
ASN A 499
GLU A 433
 None
 0.89A 3kpdB-2cvtA:
undetectable		 3kpdB-2cvtA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 573
ILE A 592
VAL A 597
TYR A 557
 None
 1.06A 3p6hA-2cvtA:
undetectable		 3p6hA-2cvtA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 5 GLU A 302
ASP A 361
ASP A 336
ASN A 411
 None
 1.39A 3vywD-2cvtA:
undetectable		 3vywD-2cvtA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ALA A 546
SER A 543
VAL A 477
ARG A 479
 None
 1.12A 4ijiH-2cvtA:
undetectable		 4ijiH-2cvtA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 246
GLY A 247
GLY A 295
ALA A 296
TYR A 285
 None
 0.98A 4rtmA-2cvtA:
undetectable		 4rtmA-2cvtA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 7 GLU A  99
LEU A 176
PHE A  94
TYR A 121
 None
 0.96A 4twdF-2cvtA:
undetectable
4twdJ-2cvtA:
undetectable		 4twdF-2cvtA:
16.82
4twdJ-2cvtA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 143
VAL A 136
ILE A 135
LEU A 156
 None
 0.91A 4xo7A-2cvtA:
3.1		 4xo7A-2cvtA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 9 SER A 543
ALA A 546
GLU A 549
ILE A 473
 None
 0.89A 4xtaA-2cvtA:
undetectable		 4xtaA-2cvtA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 143
HIS A  87
VAL A 136
ILE A 135
LEU A 156
 None
 1.13A 4yvpB-2cvtA:
3.4		 4yvpB-2cvtA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EUM_B_ACTB603_0
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 4 ALA A 325
ASN A 280
ARG A 315
ILE A 314
 None
 1.17A 5eumB-2cvtA:
0.8		 5eumB-2cvtA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 353
ILE A 422
SER A 257
 None
 0.75A 5fsaA-2cvtA:
undetectable		 5fsaA-2cvtA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 170
VAL A 124
VAL A 174
ALA A 175
LEU A 176
 None
 0.91A 5kpcA-2cvtA:
undetectable		 5kpcA-2cvtA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 542
PHE A 536
ILE A 706
VAL A 509
ALA A 474
 None
 1.09A 5nukA-2cvtA:
undetectable		 5nukA-2cvtA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 341
PRO A 335
PHE A 367
GLU A 368
 None
 1.42A 5odqA-2cvtA:
undetectable		 5odqA-2cvtA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 541
GLU A 537
TRP A 583
 None
 1.09A 5odqD-2cvtA:
2.0		 5odqD-2cvtA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 541
GLU A 537
TRP A 583
 None
 1.20A 5odrD-2cvtA:
undetectable		 5odrD-2cvtA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 272
GLY A 271
SER A 257
SER A 352
 None
 1.29A 5uunA-2cvtA:
2.0		 5uunA-2cvtA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 272
GLY A 271
SER A 257
SER A 352
 None
 1.27A 5uunB-2cvtA:
undetectable		 5uunB-2cvtA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 179
ASN A 482
VAL A 477
LEU A 192
 None
 1.30A 5xdhA-2cvtA:
undetectable
5xdhC-2cvtA:
0.0		 5xdhA-2cvtA:
6.51
5xdhC-2cvtA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 442
ASN A 499
ASN A 599
ILE A 485
 None
 1.16A 6h7uA-2cvtA:
undetectable		 6h7uA-2cvtA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		4 / 8 VAL A 484
ASN A 488
ASN A 207
PRO A 213
 None
 1.12A 6hzpA-2cvtA:
2.1		 6hzpA-2cvtA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1
(Saccharomyces
cerevisiae) 		3 / 3 THR A 478
GLU A 433
ASN A 599
 None
 0.85A 6nj9K-2cvtA:
undetectable		 6nj9K-2cvtA:
19.47