SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cw3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		3 / 3 ARG A 101
ILE A 163
TRP A 137
 None
 1.18A 1qomA-2cw3A:
undetectable		 1qomA-2cw3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		4 / 7 TYR A  32
HIS A  81
HIS A  35
TYR A  39
 None
FE  A 524 (-3.1A)
None
None
 1.22A 2ombC-2cw3A:
undetectable
2ombD-2cw3A:
undetectable		 2ombC-2cw3A:
22.59
2ombD-2cw3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		6 / 12 GLY A  76
LEU A  59
TRP A 171
ASN A  73
ALA A  74
VAL A  71
 None
 1.46A 3av6A-2cw3A:
undetectable		 3av6A-2cw3A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		4 / 6 TYR A 186
HIS A  31
HIS A  81
TYR A  84
 None
FE  A 524 (-3.1A)
FE  A 524 (-3.1A)
None
 1.45A 4df2A-2cw3A:
undetectable		 4df2A-2cw3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		4 / 5 ARG A  66
VAL A  60
LEU A 156
SER A 157
 None
 1.27A 4e1gA-2cw3A:
undetectable		 4e1gA-2cw3A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		5 / 12 TYR A  84
SER A  87
TRP A  85
THR A  27
TYR A 186
 None
 1.45A 5dsgA-2cw3A:
undetectable		 5dsgA-2cw3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		5 / 12 TYR A  84
SER A  87
TRP A  85
THR A  27
TYR A 186
 None
 1.48A 5dsgB-2cw3A:
undetectable		 5dsgB-2cw3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		3 / 3 ALA A 199
ASN A 202
LEU A 203
 None
 0.41A 5i1nC-2cw3A:
undetectable		 5i1nC-2cw3A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		3 / 3 ALA A 199
ASN A 202
LEU A 203
 None
 0.26A 5i1nB-2cw3A:
undetectable		 5i1nB-2cw3A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		3 / 3 ALA A 199
ASN A 202
LEU A 203
 None
 0.30A 5i1oC-2cw3A:
undetectable		 5i1oC-2cw3A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		3 / 3 ALA A 199
ASN A 202
LEU A 203
 None
 0.26A 5i1oA-2cw3A:
undetectable		 5i1oA-2cw3A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		3 / 3 ALA A 199
ASN A 202
LEU A 203
 None
 0.27A 5i1pA-2cw3A:
undetectable		 5i1pA-2cw3A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2cw3 IRON SUPEROXIDE
DISMUTASE
(Perkinsus
marinus) 		3 / 3 ALA A 199
ASN A 202
LEU A 203
 None
 0.27A 5i1pD-2cw3A:
undetectable		 5i1pD-2cw3A:
11.02