SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cw9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 2cw9 TRANSLOCASE OF INNER
MITOCHONDRIAL
MEMBRANE
(Homo
sapiens) 		4 / 8 TYR A 348
LEU A 336
ASP A 337
LYS A 340
 None
 0.86A 3lsfH-2cw9A:
undetectable		 3lsfH-2cw9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 2cw9 TRANSLOCASE OF INNER
MITOCHONDRIAL
MEMBRANE
(Homo
sapiens) 		4 / 7 TYR A 348
LEU A 336
ASP A 337
LYS A 340
 None
 0.90A 3lslA-2cw9A:
undetectable
3lslD-2cw9A:
undetectable		 3lslA-2cw9A:
21.83
3lslD-2cw9A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 2cw9 TRANSLOCASE OF INNER
MITOCHONDRIAL
MEMBRANE
(Homo
sapiens) 		4 / 7 TYR A 348
LEU A 336
ASP A 337
LYS A 340
 None
 0.91A 3lslA-2cw9A:
undetectable
3lslD-2cw9A:
undetectable		 3lslA-2cw9A:
21.83
3lslD-2cw9A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 2cw9 TRANSLOCASE OF INNER
MITOCHONDRIAL
MEMBRANE
(Homo
sapiens) 		4 / 6 LEU A 339
LEU A 336
GLU A 335
ILE A 355
 None
 0.88A 4ww7A-2cw9A:
2.8		 4ww7A-2cw9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2cw9 TRANSLOCASE OF INNER
MITOCHONDRIAL
MEMBRANE
(Homo
sapiens) 		3 / 3 ASP A 373
PHE A 272
ARG A 418
 None
 0.89A 5yw0A-2cw9A:
undetectable		 5yw0A-2cw9A:
18.91