SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cx4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		5 / 12 ALA A  43
ASP A  76
LEU A  81
PHE A  84
LEU A  90
 None
 1.23A 1ddrB-2cx4A:
undetectable		 1ddrB-2cx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 PRO A  42
PRO A  47
CYH A  49
ARG A 122
 None
 0.38A 1h4oB-2cx4A:
21.1		 1h4oB-2cx4A:
28.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 PRO A  42
PRO A  47
CYH A  49
ARG A 122
 None
 0.36A 1h4oG-2cx4A:
21.0		 1h4oG-2cx4A:
28.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		5 / 12 ALA A  43
ASP A  76
LEU A  81
PHE A  84
LEU A  90
 None
 1.20A 1jolA-2cx4A:
undetectable		 1jolA-2cx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		5 / 11 ALA A  43
ASP A  76
LEU A  81
PHE A  84
LEU A  90
 None
 1.14A 1jomA-2cx4A:
undetectable		 1jomA-2cx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 PRO A  42
PRO A  47
CYH A  49
ARG A 122
 None
 0.36A 1oc3A-2cx4A:
20.9		 1oc3A-2cx4A:
28.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 PRO A  42
PRO A  47
VAL A  48
ARG A 122
 None
 0.48A 2v32C-2cx4A:
20.5
2v32D-2cx4A:
22.9		 2v32C-2cx4A:
24.80
2v32D-2cx4A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 PRO A  42
PRO A  47
VAL A  48
ARG A 122
 None
 0.55A 2v41C-2cx4A:
22.9
2v41D-2cx4A:
23.1		 2v41C-2cx4A:
24.80
2v41D-2cx4A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 PRO A  42
PRO A  47
VAL A  48
ARG A 122
 None
 0.54A 2v41C-2cx4A:
22.9
2v41D-2cx4A:
23.1		 2v41C-2cx4A:
24.80
2v41D-2cx4A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 PRO A  42
PRO A  47
VAL A  48
ARG A 122
 None
 0.54A 2v41G-2cx4A:
20.4
2v41H-2cx4A:
20.5		 2v41G-2cx4A:
24.80
2v41H-2cx4A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 6 THR A  55
VAL A 151
VAL A  70
VAL A  37
 None
 0.97A 2z97A-2cx4A:
undetectable		 2z97A-2cx4A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		4 / 8 ALA A  44
PHE A  45
THR A  50
LEU A  53
 None
 0.95A 3hrdA-2cx4A:
undetectable
3hrdB-2cx4A:
undetectable		 3hrdA-2cx4A:
19.29
3hrdB-2cx4A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		3 / 3 GLU A 145
GLU A  52
TRP A 137
 None
 1.32A 3hrdA-2cx4A:
undetectable
3hrdE-2cx4A:
undetectable
3hrdF-2cx4A:
undetectable		 3hrdA-2cx4A:
19.29
3hrdE-2cx4A:
19.29
3hrdF-2cx4A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2cx4 BACTERIOFERRITIN
COMIGRATORY PROTEIN
(Aeropyrum
pernix) 		5 / 11 ALA A  43
ASP A  76
LEU A  81
PHE A  84
LEU A  90
 None
 1.23A 4i1nA-2cx4A:
undetectable		 4i1nA-2cx4A:
22.35