SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cx7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		4 / 5 ARG A  38
ALA A  36
LYS A 105
GLU A 103
 None
 1.15A 1e7cA-2cx7A:
undetectable		 1e7cA-2cx7A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		3 / 3 LEU A 122
TRP A  56
TYR A 115
 None
 0.75A 3aicA-2cx7A:
undetectable		 3aicA-2cx7A:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		3 / 3 LEU A 122
TRP A  56
TYR A 115
 None
 0.81A 3aicF-2cx7A:
undetectable		 3aicF-2cx7A:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		5 / 11 LEU A 102
ALA A  96
LEU A  94
ALA A 119
VAL A 123
 None
 0.93A 3e22B-2cx7A:
undetectable		 3e22B-2cx7A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		5 / 11 LEU A 102
ALA A  96
LEU A  94
ALA A 119
VAL A 123
 None
 0.91A 3e22D-2cx7A:
undetectable		 3e22D-2cx7A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		4 / 8 GLU A  20
GLU A  18
LYS A  15
ARG A  14
 None
 0.99A 4bqfB-2cx7A:
undetectable		 4bqfB-2cx7A:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		3 / 3 VAL A  49
GLY A  68
LYS A  47
 None
 0.69A 4k50A-2cx7A:
undetectable		 4k50A-2cx7A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		3 / 3 VAL A  49
GLY A  68
LYS A  47
 None
 0.65A 4k50E-2cx7A:
undetectable		 4k50E-2cx7A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 2cx7 STEROL CARRIER
PROTEIN 2
(Thermus
thermophilus) 		5 / 12 GLY A  89
GLU A  85
LEU A  35
LEU A  33
ALA A 119
 None
 1.16A 4wcxC-2cx7A:
undetectable		 4wcxC-2cx7A:
13.08