SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cxj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVD_B_SAMB601_1 (CATECHOL-O-METHYLTRA NSFERASE)	2cxj	S100 CALCIUM-BINDING PROTEIN A13 (Mus musculus)	3 / 3	SER A 69 GLU A 86 ASP A 52	None	0.78A	2avdB-2cxjA: undetectable	2avdB-2cxjA: 17.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2KOT_A_ANWA99_0 (PROTEIN S100-A13)	2cxj	S100 CALCIUM-BINDING PROTEIN A13 (Mus musculus)	4 / 7	VAL A 16 THR A 19 PHE A 21 THR A 22	None	1.27A	2kotA-2cxjA: 3.7	2kotA-2cxjA: 82.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KSZ_A_CYSA620_0 (LACTOPEROXIDASE)	2cxj	S100 CALCIUM-BINDING PROTEIN A13 (Mus musculus)	3 / 3	ARG A 78 GLU A 82 PHE A 21	None	0.96A	4kszA-2cxjA: undetectable	4kszA-2cxjA: 12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJL_A_ERYA1101_0 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	2cxj	S100 CALCIUM-BINDING PROTEIN A13 (Mus musculus)	5 / 12	SER A 32 PHE A 23 GLU A 86 LEU A 41 GLY A 81	None	1.49A	4zjlA-2cxjA: undetectable	4zjlA-2cxjA: 7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HJI_A_ADNA401_1 (TRNA (GUANINE(37)-N1)-MET HYLTRANSFERASE TRM5A)	2cxj	S100 CALCIUM-BINDING PROTEIN A13 (Mus musculus)	5 / 11	LEU A 41 GLY A 81 GLU A 82 ASN A 66 VAL A 16	None	1.19A	5hjiA-2cxjA: undetectable	5hjiA-2cxjA: 15.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AVD_B_SAMB601_1","CATECHOL-O-METHYLTRANSFERASE","2cxj","S100 CALCIUM-BINDING PROTEIN A13","Mus musculus",3,"SER A  69;GLU A  86;ASP A  52","None","0.78A","2avdB-2cxjA:undetectable","2avdB-2cxjA:17.90"],["2KOT_A_ANWA99_0","PROTEIN S100-A13","2cxj","S100 CALCIUM-BINDING PROTEIN A13","Mus musculus",4,"VAL A  16;THR A  19;PHE A  21;THR A  22","None","1.27A","2kotA-2cxjA:3.7","2kotA-2cxjA:82.65"],["4KSZ_A_CYSA620_0","LACTOPEROXIDASE","2cxj","S100 CALCIUM-BINDING PROTEIN A13","Mus musculus",3,"ARG A  78;GLU A  82;PHE A  21","None","0.96A","4kszA-2cxjA:undetectable","4kszA-2cxjA:12.64"],["4ZJL_A_ERYA1101_0","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","2cxj","S100 CALCIUM-BINDING PROTEIN A13","Mus musculus",5,"SER A  32;PHE A  23;GLU A  86;LEU A  41;GLY A  81","None","1.49A","4zjlA-2cxjA:undetectable","4zjlA-2cxjA:7.04"],["5HJI_A_ADNA401_1","TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE TRM5A","2cxj","S100 CALCIUM-BINDING PROTEIN A13","Mus musculus",5,"LEU A  41;GLY A  81;GLU A  82;ASN A  66;VAL A  16","None","1.19A","5hjiA-2cxjA:undetectable","5hjiA-2cxjA:15.06"]]