SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cy4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2cy4 EPIDERMAL GROWTH
FACTOR RECEPTOR
PATHWAY SUBSTRATE
8-LIKE PROTEIN 1
(Mus
musculus) 		3 / 3 SER A  92
HIS A  40
ASP A 133
 None
 0.77A 2oxtA-2cy4A:
undetectable		 2oxtA-2cy4A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 2cy4 EPIDERMAL GROWTH
FACTOR RECEPTOR
PATHWAY SUBSTRATE
8-LIKE PROTEIN 1
(Mus
musculus) 		4 / 6 ILE A 151
ARG A 148
LEU A 120
LEU A 155
 None
 0.92A 2rlfA-2cy4A:
undetectable
2rlfD-2cy4A:
undetectable		 2rlfA-2cy4A:
11.43
2rlfD-2cy4A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2cy4 EPIDERMAL GROWTH
FACTOR RECEPTOR
PATHWAY SUBSTRATE
8-LIKE PROTEIN 1
(Mus
musculus) 		4 / 6 VAL A  85
LEU A  78
HIS A 135
LEU A 120
 None
 0.88A 3kp6A-2cy4A:
undetectable
3kp6B-2cy4A:
undetectable		 3kp6A-2cy4A:
22.99
3kp6B-2cy4A:
22.99