SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		4 / 5 GLY A 139
LEU A 138
THR A 112
VAL A  82
 None
 1.10A 1ekjF-2cy9A:
undetectable
1ekjG-2cy9A:
undetectable		 1ekjF-2cy9A:
19.81
1ekjG-2cy9A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.36A 1fohA-2cy9A:
undetectable		 1fohA-2cy9A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.37A 1fohB-2cy9A:
undetectable		 1fohB-2cy9A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.35A 1fohC-2cy9A:
undetectable		 1fohC-2cy9A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.35A 1fohD-2cy9A:
undetectable		 1fohD-2cy9A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.38A 1pn0A-2cy9A:
undetectable		 1pn0A-2cy9A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.36A 1pn0B-2cy9A:
undetectable		 1pn0B-2cy9A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.33A 1pn0C-2cy9A:
undetectable		 1pn0C-2cy9A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 10 MET A  86
VAL A  64
ILE A  88
TYR A  90
GLY A  58
 None
 1.34A 1pn0D-2cy9A:
undetectable		 1pn0D-2cy9A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 2cy9 THIOESTERASE
SUPERFAMILY MEMBER 2
(Mus
musculus) 		5 / 12 LEU A  55
ASN A  50
LEU A  59
GLY A  57
LEU A 120
 None
 1.05A 5uc1B-2cy9A:
undetectable		 5uc1B-2cy9A:
25.64