SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2czo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ALA A 331
LEU A 328
VAL A 393
MET A 392
 None
 0.91A 1hk2A-2czoA:
undetectable		 1hk2A-2czoA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 8 GLN A 319
LEU A 373
TYR A 376
LEU A 396
 None
 0.96A 1hk3A-2czoA:
undetectable		 1hk3A-2czoA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.25A 2y69C-2czoA:
undetectable
2y69J-2czoA:
undetectable		 2y69C-2czoA:
20.61
2y69J-2czoA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.28A 2y69P-2czoA:
undetectable
2y69W-2czoA:
undetectable		 2y69P-2czoA:
20.61
2y69W-2czoA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.14A 3ablP-2czoA:
undetectable
3ablW-2czoA:
undetectable		 3ablP-2czoA:
20.61
3ablW-2czoA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.26A 3abmC-2czoA:
undetectable
3abmJ-2czoA:
undetectable		 3abmC-2czoA:
20.61
3abmJ-2czoA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.28A 3abmP-2czoA:
undetectable
3abmW-2czoA:
undetectable		 3abmP-2czoA:
20.61
3abmW-2czoA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.19A 3ag3C-2czoA:
undetectable
3ag3J-2czoA:
undetectable		 3ag3C-2czoA:
20.61
3ag3J-2czoA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 320
ARG A 316
TYR A 317
 None
 0.83A 5a7mA-2czoA:
undetectable		 5a7mA-2czoA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 320
ARG A 316
TYR A 317
 None
 0.82A 5a7mB-2czoA:
undetectable		 5a7mB-2czoA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.18A 5wauC-2czoA:
undetectable
5wauJ-2czoA:
undetectable		 5wauC-2czoA:
20.61
5wauJ-2czoA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.21A 5wauc-2czoA:
undetectable
5wauj-2czoA:
undetectable		 5wauc-2czoA:
20.61
5wauj-2czoA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.24A 5xdqC-2czoA:
undetectable
5xdqJ-2czoA:
undetectable		 5xdqC-2czoA:
20.61
5xdqJ-2czoA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2czo BUD EMERGENCE
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 300
PHE A 321
LEU A 396
PHE A 397
 None
 1.25A 5xdqP-2czoA:
undetectable
5xdqW-2czoA:
undetectable		 5xdqP-2czoA:
20.61
5xdqW-2czoA:
12.90