SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2czt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 12 PHE A  34
TRP A  43
VAL A  69
LEU A  79
VAL A 120
 None
 0.74A 1epbA-2cztA:
18.4		 1epbA-2cztA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 12 PHE A  34
TRP A  43
VAL A  69
VAL A 120
ALA A 129
 None
 0.45A 1epbA-2cztA:
18.4		 1epbA-2cztA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		6 / 12 PHE A  34
TRP A  43
VAL A  69
LEU A  79
VAL A 120
ALA A 129
 None
 0.66A 1epbB-2cztA:
18.5		 1epbB-2cztA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 12 PHE A  34
VAL A  69
LEU A  79
VAL A 120
ALA A 123
 None
 0.99A 1epbB-2cztA:
18.5		 1epbB-2cztA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 12 GLY A 100
ALA A  99
VAL A 118
GLY A  76
VAL A 120
 None
 0.91A 1hsgB-2cztA:
undetectable		 1hsgB-2cztA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 11 GLY A 100
ALA A  99
VAL A 118
GLY A  76
VAL A 120
 None
 0.98A 1hxwB-2cztA:
undetectable		 1hxwB-2cztA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 7 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.59A 1usqA-2cztA:
undetectable		 1usqA-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 1usqB-2cztA:
undetectable		 1usqB-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.60A 1usqC-2cztA:
undetectable		 1usqC-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.59A 1usqD-2cztA:
undetectable		 1usqD-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.61A 1usqE-2cztA:
undetectable		 1usqE-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 7 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.59A 1usqF-2cztA:
undetectable		 1usqF-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 2jkjA-2cztA:
undetectable		 2jkjA-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 2jkjB-2cztA:
undetectable		 2jkjB-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 2jkjC-2cztA:
undetectable		 2jkjC-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 5 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 2jkjD-2cztA:
undetectable		 2jkjD-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 7 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.57A 2jkjE-2cztA:
undetectable		 2jkjE-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 5 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 2jkjF-2cztA:
undetectable		 2jkjF-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 7 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.59A 2jklA-2cztA:
undetectable		 2jklA-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 6 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.59A 2jklB-2cztA:
undetectable		 2jklB-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 7 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 2jklC-2cztA:
undetectable		 2jklC-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 7 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.59A 2jklE-2cztA:
undetectable		 2jklE-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 7 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.60A 2jklF-2cztA:
undetectable		 2jklF-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 12 GLY A 100
ALA A  99
VAL A 118
GLY A  76
VAL A 120
 None
 0.87A 2r5pB-2cztA:
undetectable		 2r5pB-2cztA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 12 GLY A 100
ALA A  99
VAL A 118
GLY A  76
VAL A 120
 None
 0.95A 3jvyA-2cztA:
undetectable		 3jvyA-2cztA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		5 / 10 GLY A 100
ALA A  99
VAL A 118
GLY A  76
VAL A 120
 None
 0.98A 3oxwA-2cztA:
undetectable		 3oxwA-2cztA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2czt PROSTAGLANDIN-H2
D-ISOMERASE
(Mus
musculus) 		4 / 5 LEU A 148
LYS A 162
LEU A 130
GLU A 122
 None
 1.28A 5weaA-2cztA:
undetectable		 5weaA-2cztA:
12.03