SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 2d04 CURCULIN
(Molineria
latifolia) 		4 / 8 ASP B  46
LYS B  28
GLY B  51
THR B  55
 None
 1.05A 2aouA-2d04B:
undetectable		 2aouA-2d04B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 2d04 NEOCULIN ACIDIC
SUBUNIT
(Molineria
latifolia) 		6 / 11 SER A  18
LEU A  31
LEU A  54
SER A   2
LEU A  16
LEU A  62
 None
 1.12A 2xn5A-2d04A:
undetectable		 2xn5A-2d04A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 2d04 CURCULIN
(Molineria
latifolia) 		5 / 11 LEU B  86
GLY B  98
LYS B  83
SER B  58
LEU B  57
 None
 1.05A 3gyqB-2d04B:
undetectable		 3gyqB-2d04B:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 2d04 NEOCULIN ACIDIC
SUBUNIT
(Molineria
latifolia) 		3 / 3 ASP A  59
ARG A  57
ASP A  76
 None
 0.86A 4fp9D-2d04A:
undetectable		 4fp9D-2d04A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 2d04 CURCULIN
(Molineria
latifolia) 		5 / 12 ASN B  30
ILE B  25
ILE B  64
SER B  43
THR B  24
 None
 1.13A 4uroD-2d04B:
undetectable		 4uroD-2d04B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 2d04 NEOCULIN ACIDIC
SUBUNIT
(Molineria
latifolia) 		5 / 10 SER A  18
LEU A  31
LEU A  54
SER A   2
LEU A  16
 None
 1.18A 4yiaA-2d04A:
undetectable		 4yiaA-2d04A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 2d04 CURCULIN
NEOCULIN ACIDIC
SUBUNIT
(Molineria
latifolia) 		4 / 5 LEU A  56
ALA A  85
LEU A   4
VAL B  95
 None
 1.10A 5cr1A-2d04A:
undetectable		 5cr1A-2d04A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 2d04 CURCULIN
NEOCULIN ACIDIC
SUBUNIT
(Molineria
latifolia) 		4 / 5 LEU B  56
ALA B  85
LEU B   4
VAL A  95
 None
 1.12A 5cr1A-2d04B:
undetectable		 5cr1A-2d04B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2d04 CURCULIN
NEOCULIN ACIDIC
SUBUNIT
(Molineria
latifolia) 		4 / 7 LEU B  86
ASN B   2
VAL A   3
GLN A  90
 None
 1.03A 5tudA-2d04B:
undetectable		 5tudA-2d04B:
12.50