SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 THR A 121
THR A 196
PRO A 198
 None
 0.85A 1a7yB-2d07A:
undetectable		 1a7yB-2d07A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 10 LEU A 132
THR A 264
ILE A 259
PHE A 189
ILE A 137
 None
 1.22A 1i18A-2d07A:
undetectable
1i18B-2d07A:
undetectable		 1i18A-2d07A:
19.13
1i18B-2d07A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 10 PHE A 189
ILE A 137
LEU A 132
THR A 264
ILE A 259
 None
 1.21A 1i18A-2d07A:
undetectable
1i18B-2d07A:
undetectable		 1i18A-2d07A:
19.13
1i18B-2d07A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 THR A 121
THR A 196
PRO A 198
 None
 0.85A 1qfiB-2d07A:
undetectable		 1qfiB-2d07A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 THR A 196
PRO A 198
THR A 121
 None
 0.84A 1unjF-2d07A:
undetectable		 1unjF-2d07A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 12 ALA A 146
GLY A 149
THR A 196
GLY A 188
LEU A 128
 None
 1.01A 2hw2A-2d07A:
undetectable		 2hw2A-2d07A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 LEU A 181
LEU A 292
PHE A 189
 None
 0.71A 2pgrA-2d07A:
undetectable		 2pgrA-2d07A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		4 / 5 SER A 272
ILE A 139
TYR A 152
GLY A 231
 None
 1.03A 3uboB-2d07A:
undetectable		 3uboB-2d07A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 LEU A 132
ASN A 191
LEU A 219
 None
 0.66A 6exiA-2d07A:
undetectable		 6exiA-2d07A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 THR A 196
ALA A 146
LYS A 148
 None
 0.68A 6fgcA-2d07A:
3.5		 6fgcA-2d07A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 2d07 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		3 / 3 THR A 196
ALA A 146
LYS A 148
 None
 0.68A 6fgdA-2d07A:
4.9		 6fgdA-2d07A:
20.00