SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		3 / 3 GLU A 168
ASN A 165
TRP A 156
 None
 1.13A 1r15C-2d13A:
3.0		 1r15C-2d13A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		3 / 3 GLU A 168
ASN A 165
TRP A 156
 None
 1.09A 1r15D-2d13A:
3.0		 1r15D-2d13A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		3 / 3 GLU A 168
ASN A 165
TRP A 156
 None
 1.10A 1r15E-2d13A:
1.8		 1r15E-2d13A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		3 / 3 GLU A 168
ASN A 165
TRP A 156
 None
 1.10A 1r15F-2d13A:
2.9		 1r15F-2d13A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		5 / 12 ALA A 181
GLY A 184
GLU A 109
ILE A 108
ALA A  98
 None
 1.06A 2plwA-2d13A:
4.2		 2plwA-2d13A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		4 / 6 LEU A  25
ILE A  64
ARG A  30
ARG A  32
 None
 0.89A 2q8hA-2d13A:
undetectable		 2q8hA-2d13A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		4 / 4 LEU A  54
ALA A 222
ILE A 203
LYS A  51
 None
 1.15A 4eixA-2d13A:
undetectable		 4eixA-2d13A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		5 / 12 MET A  37
VAL A  35
VAL A 111
LEU A  82
VAL A 119
 None
 1.46A 4m11D-2d13A:
undetectable		 4m11D-2d13A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		3 / 3 TYR A  11
ALA A  24
LEU A  25
 None
 0.43A 6ag0C-2d13A:
undetectable		 6ag0C-2d13A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		4 / 8 GLU A 106
TRP A 124
THR A 121
ASN A 110
 None
 1.14A 6c71B-2d13A:
undetectable		 6c71B-2d13A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		3 / 3 ARG A  30
LYS A  90
TYR A  33
 None
 1.31A 6gnaA-2d13A:
3.0		 6gnaA-2d13A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2d13 HYPOTHETICAL PROTEIN
PH1257
(Pyrococcus
horikoshii) 		3 / 3 ARG A  30
LYS A  90
TYR A  33
 None
 1.31A 6gnbA-2d13A:
3.0		 6gnbA-2d13A:
22.59