SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d1h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 2d1h 109AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR
(Sulfurisphaera
tokodaii) 		5 / 8 LEU A  48
LYS A  29
GLU A  32
ALA A  25
THR A  22
 None
 1.43A 1ie4B-2d1hA:
undetectable
1ie4D-2d1hA:
undetectable		 1ie4B-2d1hA:
23.62
1ie4D-2d1hA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 2d1h 109AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR
(Sulfurisphaera
tokodaii) 		5 / 10 TYR A  17
ILE A  13
LEU A  65
VAL A  66
LEU A  60
 None
 1.14A 2w98A-2d1hA:
undetectable		 2w98A-2d1hA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2d1h 109AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR
(Sulfurisphaera
tokodaii) 		3 / 3 LYS A   3
LYS A  29
VAL A  31
 None
 1.01A 3brfA-2d1hA:
undetectable		 3brfA-2d1hA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 2d1h 109AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  28
GLU A   7
GLU A  12
ILE A  13
 None
 0.96A 3s56B-2d1hA:
undetectable		 3s56B-2d1hA:
23.08