SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 GLY A 317
THR A 529
VAL A 243
ALA A 350
GLY A 343
 AMP  A1001 ( 4.3A)
AMP  A1001 ( 4.7A)
None
None
None
 0.91A 1bx4A-2d1qA:
undetectable		 1bx4A-2d1qA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		4 / 6 TYR A 282
ASP A  52
VAL A 265
GLY A  50
 None
 1.20A 1ekjC-2d1qA:
undetectable
1ekjD-2d1qA:
undetectable		 1ekjC-2d1qA:
18.96
1ekjD-2d1qA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 GLY A 236
GLY A 261
ASP A  52
ALA A 238
VAL A 239
 None
 1.13A 1jg2A-2d1qA:
undetectable		 1jg2A-2d1qA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 GLY A 261
ASP A  52
THR A 237
ALA A 238
VAL A 239
 None
 1.19A 1jg2A-2d1qA:
undetectable		 1jg2A-2d1qA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 PRO A  93
GLY A 103
VAL A  76
ALA A  81
ALA A 105
 None
 1.26A 1nw5A-2d1qA:
undetectable		 1nw5A-2d1qA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		4 / 4 HIS A 223
VAL A 368
THR A 348
LEU A 344
 None
None
None
AMP  A1001 (-4.0A)
 1.38A 1oq5A-2d1qA:
undetectable		 1oq5A-2d1qA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		4 / 4 HIS A 223
VAL A 368
THR A 348
LEU A 420
 None
 1.43A 1oq5A-2d1qA:
undetectable		 1oq5A-2d1qA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 11 LEU A  82
THR A 107
ILE A 153
ILE A 151
VAL A 152
 None
 1.14A 1pkvA-2d1qA:
undetectable
1pkvB-2d1qA:
undetectable		 1pkvA-2d1qA:
12.71
1pkvB-2d1qA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 11 ILE A 151
VAL A 152
LEU A  82
THR A 107
ILE A 153
 None
 1.13A 1pkvA-2d1qA:
undetectable
1pkvB-2d1qA:
undetectable		 1pkvA-2d1qA:
12.71
1pkvB-2d1qA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 8 ALA A  68
ILE A 100
GLY A  97
ILE A  92
ALA A 180
 CSO  A  64 ( 3.4A)
None
None
None
CSO  A  64 ( 3.8A)
 1.09A 1sguA-2d1qA:
undetectable		 1sguA-2d1qA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 ARG A 225
TYR A  32
LYS A  31
 None
 0.99A 1uujB-2d1qA:
undetectable		 1uujB-2d1qA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 ARG A 515
TYR A 446
LYS A 447
 None
 0.97A 1uujB-2d1qA:
undetectable		 1uujB-2d1qA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 ILE A 351
GLY A 343
GLY A 317
VAL A 394
LEU A 399
 None
None
AMP  A1001 ( 4.3A)
None
None
 0.92A 1vptA-2d1qA:
undetectable		 1vptA-2d1qA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 9 GLY A  26
ALA A  25
LEU A  98
PHE A 221
LEU A 196
 None
 1.04A 1y7iA-2d1qA:
undetectable		 1y7iA-2d1qA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		4 / 7 ASP A 438
ALA A 454
GLY A 470
ILE A 537
 None
 0.88A 2fxdB-2d1qA:
undetectable		 2fxdB-2d1qA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.79A 2ieoA-2d1qA:
undetectable		 2ieoA-2d1qA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.87A 2q63A-2d1qA:
undetectable		 2q63A-2d1qA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 THR A 254
VAL A 243
VAL A 242
VAL A 239
VAL A 264
 None
 1.47A 2qboA-2d1qA:
undetectable		 2qboA-2d1qA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 GLU A  88
ASP A  52
TYR A 282
 None
 0.67A 2yvlB-2d1qA:
undetectable		 2yvlB-2d1qA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 ALA A  25
LEU A 255
LEU A 196
LEU A  82
ALA A  96
 None
 1.11A 3dfrA-2d1qA:
undetectable		 3dfrA-2d1qA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 11 GLY A 318
ALA A 319
ILE A 532
GLY A 527
LEU A 528
 AMP  A1001 (-3.5A)
None
None
None
None
 0.92A 3em4U-2d1qA:
undetectable		 3em4U-2d1qA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		4 / 8 GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.60A 3em6A-2d1qA:
undetectable		 3em6A-2d1qA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		4 / 8 PHE A 371
VAL A 367
ILE A  10
GLY A  13
 None
 0.95A 3hjoA-2d1qA:
undetectable		 3hjoA-2d1qA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.90A 3jw2A-2d1qA:
undetectable		 3jw2A-2d1qA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.83A 3lzvA-2d1qA:
undetectable		 3lzvA-2d1qA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.89A 3oxwA-2d1qA:
undetectable		 3oxwA-2d1qA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.82A 3oxwC-2d1qA:
undetectable		 3oxwC-2d1qA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.87A 3oy4B-2d1qA:
undetectable		 3oy4B-2d1qA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 ILE A 314
LEU A 289
VAL A 242
LEU A 279
ALA A  47
 None
 1.17A 3ozuA-2d1qA:
2.6		 3ozuA-2d1qA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 ARG A 339
ARG A 220
ASP A 226
 None
 0.95A 3wipG-2d1qA:
undetectable
3wipH-2d1qA:
undetectable		 3wipG-2d1qA:
18.07
3wipH-2d1qA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.86A 4dqbB-2d1qA:
undetectable		 4dqbB-2d1qA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.86A 4dqeB-2d1qA:
undetectable		 4dqeB-2d1qA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.89A 4dqfB-2d1qA:
undetectable		 4dqfB-2d1qA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.87A 4dqhB-2d1qA:
undetectable		 4dqhB-2d1qA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 9 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.89A 4q1wA-2d1qA:
undetectable		 4q1wA-2d1qA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 11 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.84A 4q1xA-2d1qA:
undetectable		 4q1xA-2d1qA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 10 LEU A 514
GLY A 470
ALA A 469
ASP A 468
VAL A 504
 None
 0.85A 4q1yA-2d1qA:
undetectable		 4q1yA-2d1qA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 ALA A 350
GLY A 318
GLY A 250
PHE A 249
TYR A 257
 None
AMP  A1001 (-3.5A)
None
None
None
 1.11A 4r29B-2d1qA:
undetectable		 4r29B-2d1qA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 ALA A 350
GLY A 318
GLY A 250
PHE A 249
TYR A 257
 None
AMP  A1001 (-3.5A)
None
None
None
 1.18A 4r29C-2d1qA:
undetectable		 4r29C-2d1qA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		4 / 8 ILE A  80
LEU A 212
LEU A  98
ILE A 217
 None
 0.88A 4r38D-2d1qA:
undetectable		 4r38D-2d1qA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 PRO A 244
GLY A 530
GLY A 318
ILE A 110
GLY A 527
 None
None
AMP  A1001 (-3.5A)
None
None
 1.00A 4yvgA-2d1qA:
undetectable		 4yvgA-2d1qA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 VAL A 368
SER A 349
MET A 400
 None
 0.86A 5ikqA-2d1qA:
undetectable		 5ikqA-2d1qA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 GLN A 164
THR A 168
ASP A 159
 None
 0.78A 5k9dA-2d1qA:
undetectable		 5k9dA-2d1qA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 GLY A 317
THR A 529
VAL A 243
ALA A 350
GLY A 343
 AMP  A1001 ( 4.3A)
AMP  A1001 ( 4.7A)
None
None
None
 0.91A 5kb6A-2d1qA:
undetectable		 5kb6A-2d1qA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 VAL A 524
ARG A 513
PRO A 483
 None
 0.86A 5koxA-2d1qA:
undetectable		 5koxA-2d1qA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 12 PRO A 244
GLY A 530
GLY A 318
ILE A 110
GLY A 527
 None
None
AMP  A1001 (-3.5A)
None
None
 0.99A 5wyqA-2d1qA:
undetectable		 5wyqA-2d1qA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		5 / 11 VAL A 325
GLY A 326
SER A 316
SER A 322
LEU A 461
 None
 1.16A 5x6yC-2d1qA:
4.4		 5x6yC-2d1qA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2d1q LUCIFERIN
4-MONOOXYGENASE
(Luciola
cruciata) 		3 / 3 LYS A 374
LEU A 399
ASP A 415
 None
 0.90A 5zv2A-2d1qA:
undetectable		 5zv2A-2d1qA:
11.15