SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2d1v TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		5 / 12 GLY A 138
ILE A 209
LEU A 166
LEU A 169
ILE A 173
 None
 0.99A 3adxB-2d1vA:
undetectable		 3adxB-2d1vA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2d1v TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		5 / 8 HIS A 167
LEU A 205
ILE A 142
VAL A 149
LEU A 158
 None
 1.35A 3kp6A-2d1vA:
3.4
3kp6B-2d1vA:
4.7		 3kp6A-2d1vA:
20.53
3kp6B-2d1vA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 2d1v TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		3 / 3 THR A 221
ASP A 199
GLU A 180
 None
 0.79A 3qowA-2d1vA:
undetectable		 3qowA-2d1vA:
15.57