SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d28'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 2d28 TYPE II SECRETION
ATPASE XPSE
(Xanthomonas
campestris) 		5 / 12 TYR C 114
ASP C 112
LEU C  62
VAL C  61
LEU C  14
 None
 1.14A 1r30A-2d28C:
undetectable		 1r30A-2d28C:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 2d28 TYPE II SECRETION
ATPASE XPSE
(Xanthomonas
campestris) 		4 / 6 PRO C 113
HIS C  54
LEU C  40
ALA C   6
 None
 0.98A 3gv1A-2d28C:
undetectable
3gv1C-2d28C:
undetectable		 3gv1A-2d28C:
18.67
3gv1C-2d28C:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 2d28 TYPE II SECRETION
ATPASE XPSE
(Xanthomonas
campestris) 		4 / 6 LEU C  40
ALA C   6
PRO C 113
HIS C  54
 None
 1.04A 3gv1A-2d28C:
undetectable
3gv1B-2d28C:
undetectable		 3gv1A-2d28C:
18.67
3gv1B-2d28C:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2d28 TYPE II SECRETION
ATPASE XPSE
(Xanthomonas
campestris) 		4 / 5 PRO C 113
ASP C 112
ILE C  10
VAL C  49
 None
 1.35A 4hytA-2d28C:
undetectable		 4hytA-2d28C:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2d28 TYPE II SECRETION
ATPASE XPSE
(Xanthomonas
campestris) 		4 / 5 LEU C  25
VAL C  11
GLU C   7
LEU C  39
 None
 1.05A 5xooB-2d28C:
undetectable		 5xooB-2d28C:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2d28 TYPE II SECRETION
ATPASE XPSE
(Xanthomonas
campestris) 		4 / 7 ARG C 137
TYR C 114
LEU C  64
VAL C 134
 None
 1.36A 6g2pA-2d28C:
undetectable		 6g2pA-2d28C:
17.42