SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d2x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.05A 1c9sN-2d2xA:
undetectable
1c9sO-2d2xA:
undetectable		 1c9sN-2d2xA:
12.47
1c9sO-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 11 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.04A 1c9sP-2d2xA:
undetectable
1c9sQ-2d2xA:
undetectable		 1c9sP-2d2xA:
12.47
1c9sQ-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 9 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.05A 1c9sQ-2d2xA:
undetectable
1c9sR-2d2xA:
undetectable		 1c9sQ-2d2xA:
12.47
1c9sR-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.03A 1c9sL-2d2xA:
undetectable
1c9sV-2d2xA:
undetectable		 1c9sL-2d2xA:
12.47
1c9sV-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 9 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.07A 1gtfD-2d2xA:
undetectable
1gtfE-2d2xA:
undetectable		 1gtfD-2d2xA:
12.47
1gtfE-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.05A 1gtfJ-2d2xA:
undetectable
1gtfK-2d2xA:
undetectable		 1gtfJ-2d2xA:
12.47
1gtfK-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 11 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.06A 1gtfQ-2d2xA:
undetectable
1gtfR-2d2xA:
undetectable		 1gtfQ-2d2xA:
12.47
1gtfR-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 9 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.07A 1gtfR-2d2xA:
undetectable
1gtfS-2d2xA:
undetectable		 1gtfR-2d2xA:
12.47
1gtfS-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 11 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.07A 1gtfS-2d2xA:
undetectable
1gtfT-2d2xA:
undetectable		 1gtfS-2d2xA:
12.47
1gtfT-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 11 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.07A 1gtnT-2d2xA:
undetectable
1gtnU-2d2xA:
undetectable		 1gtnT-2d2xA:
12.47
1gtnU-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 6 PHE A 220
ILE A 218
LYS A 225
ALA A 224
 None
 1.20A 1hk2A-2d2xA:
1.3		 1hk2A-2d2xA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		3 / 3 THR A  79
LEU A  83
LEU A  90
 None
 0.60A 1mz9C-2d2xA:
undetectable		 1mz9C-2d2xA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.05A 1utdE-2d2xA:
undetectable
1utdF-2d2xA:
undetectable		 1utdE-2d2xA:
12.47
1utdF-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.03A 1utdH-2d2xA:
undetectable
1utdI-2d2xA:
undetectable		 1utdH-2d2xA:
12.47
1utdI-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 11 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.09A 1utdS-2d2xA:
undetectable
1utdT-2d2xA:
undetectable		 1utdS-2d2xA:
12.47
1utdT-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 THR A 129
THR A 128
ILE A  49
GLY A 104
THR A 106
 GOL  A 607 (-3.3A)
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
 1.06A 1utdU-2d2xA:
undetectable
1utdV-2d2xA:
undetectable		 1utdU-2d2xA:
12.47
1utdV-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 11 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.11A 1utdL-2d2xA:
undetectable
1utdV-2d2xA:
undetectable		 1utdL-2d2xA:
12.47
1utdV-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 8 GLY A 299
PHE A 130
ILE A 298
ASN A 204
 None
 1.06A 2a8tB-2d2xA:
undetectable		 2a8tB-2d2xA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 12 LEU A 368
LEU A 301
ILE A 364
LEU A 189
VAL A 185
 None
 1.16A 2hrcA-2d2xA:
undetectable		 2hrcA-2d2xA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 12 LEU A 368
LEU A 301
ILE A 364
LEU A 189
VAL A 185
 None
 1.15A 2hrcB-2d2xA:
2.5		 2hrcB-2d2xA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 8 THR A 353
PRO A 354
VAL A 355
ALA A 277
 None
 1.16A 2v41G-2d2xA:
undetectable
2v41H-2d2xA:
undetectable		 2v41G-2d2xA:
24.24
2v41H-2d2xA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 LEU A 351
VAL A 228
ILE A 190
LEU A 191
PHE A 242
 None
 1.11A 3fl9A-2d2xA:
2.1		 3fl9A-2d2xA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 12 LEU A 351
VAL A 228
ILE A 190
LEU A 191
PHE A 242
 None
 1.11A 3fl9B-2d2xA:
undetectable		 3fl9B-2d2xA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 LEU A 351
VAL A 228
ILE A 190
LEU A 191
PHE A 242
 None
 1.12A 3fl9E-2d2xA:
undetectable		 3fl9E-2d2xA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 LEU A 351
VAL A 228
ILE A 190
LEU A 191
PHE A 242
 None
 1.11A 3fl9F-2d2xA:
undetectable		 3fl9F-2d2xA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 7 GLU A 200
VAL A 185
VAL A 341
ALA A 290
 None
 0.98A 3kp6B-2d2xA:
undetectable		 3kp6B-2d2xA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		3 / 4 SER A 308
GLY A 269
GLU A 243
 None
None
CO  A 604 ( 4.0A)
 0.68A 3raeA-2d2xA:
undetectable
3raeC-2d2xA:
2.3		 3raeA-2d2xA:
21.44
3raeC-2d2xA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 ILE A 241
LEU A 351
GLY A 342
GLY A 340
SER A 339
 None
 1.12A 4bwlC-2d2xA:
2.8		 4bwlC-2d2xA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 8 LEU A 105
GLY A 104
GLU A 253
ALA A 179
 CO  A 603 (-4.2A)
GOL  A 607 (-4.1A)
None
GOL  A 607 ( 4.8A)
 0.73A 4rjdA-2d2xA:
undetectable
4rjdB-2d2xA:
undetectable		 4rjdA-2d2xA:
10.31
4rjdB-2d2xA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 6 ILE A 124
PHE A 161
ARG A 160
GLU A  33
 None
 1.31A 4zzcA-2d2xA:
undetectable
4zzcB-2d2xA:
undetectable		 4zzcA-2d2xA:
22.25
4zzcB-2d2xA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 6 ILE A 124
PHE A 161
ARG A 160
GLU A  33
 None
 1.34A 4zzcB-2d2xA:
undetectable
4zzcC-2d2xA:
undetectable		 4zzcB-2d2xA:
22.25
4zzcC-2d2xA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 9 SER A 136
ALA A 133
ALA A 164
GLY A 104
GLY A 103
 None
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-3.1A)
 1.07A 5d0xK-2d2xA:
undetectable
5d0xL-2d2xA:
undetectable		 5d0xK-2d2xA:
18.70
5d0xL-2d2xA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 9 SER A 136
ALA A 133
ALA A 164
GLY A 104
GLY A 103
 None
None
None
GOL  A 607 (-4.1A)
CO  A 603 (-3.1A)
 1.05A 5d0xY-2d2xA:
undetectable
5d0xZ-2d2xA:
undetectable		 5d0xY-2d2xA:
18.70
5d0xZ-2d2xA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5eevA-2d2xA:
undetectable
5eevB-2d2xA:
undetectable		 5eevA-2d2xA:
12.47
5eevB-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5eewA-2d2xA:
undetectable
5eewB-2d2xA:
undetectable		 5eewA-2d2xA:
12.47
5eewB-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5eexA-2d2xA:
undetectable
5eexB-2d2xA:
undetectable		 5eexA-2d2xA:
12.47
5eexB-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5eeyA-2d2xA:
undetectable
5eeyB-2d2xA:
undetectable		 5eeyA-2d2xA:
12.47
5eeyB-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5eezA-2d2xA:
undetectable
5eezB-2d2xA:
undetectable		 5eezA-2d2xA:
12.47
5eezB-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5ef0A-2d2xA:
undetectable
5ef0B-2d2xA:
undetectable		 5ef0A-2d2xA:
12.47
5ef0B-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5ef1A-2d2xA:
undetectable
5ef1B-2d2xA:
undetectable		 5ef1A-2d2xA:
12.47
5ef1B-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5ef2A-2d2xA:
undetectable
5ef2B-2d2xA:
undetectable		 5ef2A-2d2xA:
12.47
5ef2B-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 10 GLY A 104
THR A 106
THR A 129
THR A 128
ILE A  49
 GOL  A 607 (-4.1A)
CO  A 603 (-4.0A)
GOL  A 607 (-3.3A)
None
None
 1.04A 5ef3A-2d2xA:
undetectable
5ef3B-2d2xA:
undetectable		 5ef3A-2d2xA:
12.47
5ef3B-2d2xA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		4 / 6 GLY A 102
THR A 128
SER A  41
VAL A 101
 CO  A 603 ( 4.2A)
None
None
None
 1.13A 5ewuA-2d2xA:
2.9		 5ewuA-2d2xA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 2d2x 2-DEOXY-SCYLLO-INOSO
SE SYNTHASE
(Bacillus
circulans) 		5 / 12 GLY A 103
ALA A 133
THR A 106
VAL A 109
PHE A  68
 CO  A 603 (-3.1A)
None
CO  A 603 (-4.0A)
None
None
 1.00A 5x6yA-2d2xA:
2.0		 5x6yA-2d2xA:
19.40