SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q9R_A_BEZA203_0 (PROTEIN OF UNKNOWN FUNCTION)	2d30	CYTIDINE DEAMINASE (Bacillus anthracis)	4 / 5	LEU A 30 GLY A 40 ILE A 75 ILE A 73	None	0.79A	2q9rA-2d30A: undetectable	2q9rA-2d30A: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FBX_A_ACTA608_0 (PUTATIVE PHOSPHOLIPASE B-LIKE 2)	2d30	CYTIDINE DEAMINASE (Bacillus anthracis)	3 / 3	GLU A 44 VAL A 43 CYH A 51	None	1.07A	3fbxA-2d30A: undetectable	3fbxA-2d30A: 13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_C_DR7C100_2 (HIV-1 PROTEASE)	2d30	CYTIDINE DEAMINASE (Bacillus anthracis)	5 / 11	ARG A 90 GLY A 27 VAL A 26 VAL A 103 ILE A 73	None	1.02A	3oxxD-2d30A: undetectable	3oxxD-2d30A: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RAE_F_LFXF101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B)	2d30	CYTIDINE DEAMINASE (Bacillus anthracis)	3 / 4	SER A 22 GLY A 27 GLU A 12	None	0.53A	3raeA-2d30A: undetectable 3raeC-2d30A: undetectable	3raeA-2d30A: 16.33 3raeC-2d30A: 23.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Q9R_A_BEZA203_0","PROTEIN OF UNKNOWN FUNCTION","2d30","CYTIDINE DEAMINASE","Bacillus anthracis",4,"LEU A  30;GLY A  40;ILE A  75;ILE A  73","None","0.79A","2q9rA-2d30A:undetectable","2q9rA-2d30A:23.04"],["3FBX_A_ACTA608_0","PUTATIVE PHOSPHOLIPASE B-LIKE 2","2d30","CYTIDINE DEAMINASE","Bacillus anthracis",3,"GLU A  44;VAL A  43;CYH A  51","None","1.07A","3fbxA-2d30A:undetectable","3fbxA-2d30A:13.31"],["3OXX_C_DR7C100_2","HIV-1 PROTEASE;HIV-1 PROTEASE","2d30","CYTIDINE DEAMINASE","Bacillus anthracis",5,"ARG A  90;GLY A  27;VAL A  26;VAL A 103;ILE A  73","None","1.02A","3oxxD-2d30A:undetectable","3oxxD-2d30A:19.72"],["3RAE_F_LFXF101_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B","2d30","CYTIDINE DEAMINASE","Bacillus anthracis",3,"SER A  22;GLY A  27;GLU A  12","None","0.53A","3raeA-2d30A:undetectable;3raeC-2d30A:undetectable","3raeA-2d30A:16.33;3raeC-2d30A:23.60"]]