SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 6 ASP A 207
LEU A 208
VAL A 209
TRP A 306
 None
 0.86A 1s9qA-2d39A:
undetectable		 1s9qA-2d39A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 6 LEU A 208
VAL A 209
TRP A 306
TYR A 220
 None
 1.00A 1s9qA-2d39A:
undetectable		 1s9qA-2d39A:
23.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J1G_F_SC2F1290_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		8 / 10 SER A 129
LEU A 145
ASP A 147
ASP A 149
THR A 150
ARG A 160
GLU A 320
LYS A 322
 None
 0.42A 2j1gE-2d39A:
33.6
2j1gF-2d39A:
33.4		 2j1gE-2d39A:
81.65
2j1gF-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 5 ASP A 163
SER A 165
LEU A 183
GLY A 184
 None
 0.19A 2j2pA-2d39A:
32.9
2j2pB-2d39A:
33.3		 2j2pA-2d39A:
81.65
2j2pB-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		6 / 8 SER A 129
LEU A 145
ASP A 147
ASP A 149
ARG A 160
GLU A 320
 None
 0.48A 2j2pA-2d39A:
32.9
2j2pB-2d39A:
33.3		 2j2pA-2d39A:
81.65
2j2pB-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		5 / 9 SER A 129
LEU A 145
ASP A 147
ASP A 149
GLU A 320
 None
 0.39A 2j2pB-2d39A:
33.3
2j2pC-2d39A:
33.2		 2j2pB-2d39A:
81.65
2j2pC-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		5 / 6 ASP A 163
SER A 165
SER A 181
LEU A 183
GLY A 184
 None
 0.25A 2j2pA-2d39A:
32.9
2j2pC-2d39A:
33.2		 2j2pA-2d39A:
81.65
2j2pC-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 6 ASP A 167
ARG A 170
ASP A 171
LYS A 259
 None
 0.57A 2j2pE-2d39A:
33.1
2j2pF-2d39A:
33.2		 2j2pE-2d39A:
81.65
2j2pF-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_E_SC2E1290_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		5 / 9 SER A 129
LEU A 145
ASP A 147
ARG A 160
GLU A 320
 None
 0.43A 2j2pD-2d39A:
33.0
2j2pE-2d39A:
33.1		 2j2pD-2d39A:
81.65
2j2pE-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		5 / 6 ASP A 163
SER A 165
SER A 181
LEU A 183
GLY A 184
 None
 0.27A 2j2pD-2d39A:
33.0
2j2pF-2d39A:
33.2		 2j2pD-2d39A:
81.65
2j2pF-2d39A:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 6 SER A 129
ASP A 147
ASP A 149
GLU A 320
 None
 0.48A 2j2pE-2d39A:
33.1
2j2pF-2d39A:
33.2		 2j2pE-2d39A:
81.65
2j2pF-2d39A:
81.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 8 PHE A 179
TYR A 169
PHE A 256
ASN A 190
 None
 1.23A 2wekA-2d39A:
undetectable		 2wekA-2d39A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 8 PHE A 179
TYR A 169
PHE A 256
ASN A 190
 None
 1.23A 2wekB-2d39A:
undetectable		 2wekB-2d39A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 7 GLY A 189
MET A 162
PHE A 168
GLY A 180
 None
 0.99A 3ko0M-2d39A:
undetectable
3ko0P-2d39A:
undetectable		 3ko0M-2d39A:
16.88
3ko0P-2d39A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 2d39 FICOLIN-1
(Homo
sapiens) 		4 / 7 PHE A 168
GLY A 290
GLY A 164
PHE A 256
 None
 0.89A 3ko0M-2d39A:
undetectable
3ko0P-2d39A:
undetectable		 3ko0M-2d39A:
16.88
3ko0P-2d39A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2d39 FICOLIN-1
(Homo
sapiens) 		5 / 12 LEU A 208
SER A 315
ASN A 305
GLN A 216
SER A 247
 None
 1.42A 4b3aA-2d39A:
undetectable		 4b3aA-2d39A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 2d39 FICOLIN-1
(Homo
sapiens) 		5 / 12 SER A 181
ASP A 163
GLY A 164
LEU A 291
MET A 294
 None
 1.42A 4pghB-2d39A:
undetectable		 4pghB-2d39A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2d39 FICOLIN-1
(Homo
sapiens) 		5 / 12 VAL A 157
VAL A 144
GLU A 320
SER A 319
VAL A 318
 None
 1.40A 6bzoC-2d39A:
undetectable		 6bzoC-2d39A:
11.31