SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ALA A 116
VAL A  43
TRP A  39
 None
 0.85A 1av2A-2d3yA:
undetectable
1av2B-2d3yA:
undetectable		 1av2A-2d3yA:
8.73
1av2B-2d3yA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 TRP A  39
ALA A 116
VAL A  43
 None
 0.79A 1av2C-2d3yA:
undetectable
1av2D-2d3yA:
undetectable		 1av2C-2d3yA:
8.73
1av2D-2d3yA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ALA A 116
VAL A  43
TRP A  39
 None
 0.83A 1w5uA-2d3yA:
undetectable
1w5uB-2d3yA:
undetectable		 1w5uA-2d3yA:
8.73
1w5uB-2d3yA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 TRP A  39
ALA A 116
VAL A  43
 None
 0.76A 1w5uA-2d3yA:
undetectable
1w5uB-2d3yA:
undetectable		 1w5uA-2d3yA:
8.73
1w5uB-2d3yA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ALA A 116
VAL A  43
TRP A  39
 None
 0.78A 2izqA-2d3yA:
undetectable
2izqB-2d3yA:
undetectable		 2izqA-2d3yA:
8.73
2izqB-2d3yA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 TRP A  39
ALA A 116
VAL A  43
 None
 0.91A 2izqC-2d3yA:
undetectable
2izqD-2d3yA:
undetectable		 2izqC-2d3yA:
8.73
2izqD-2d3yA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A  56
PRO A 122
LEU A 127
ALA A 157
 None
 1.07A 2vcvA-2d3yA:
undetectable		 2vcvA-2d3yA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A  56
PRO A 122
LEU A 127
ALA A 157
 None
 0.99A 2vcvL-2d3yA:
undetectable		 2vcvL-2d3yA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 5 SER A  77
ARG A 114
GLY A  45
GLU A 137
 ACT  A 222 ( 4.2A)
None
None
None
 1.27A 3k9fA-2d3yA:
undetectable
3k9fB-2d3yA:
undetectable
3k9fC-2d3yA:
2.8		 3k9fA-2d3yA:
17.90
3k9fB-2d3yA:
17.90
3k9fC-2d3yA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 8 LEU A  81
VAL A 148
LEU A  55
VAL A 209
LEU A 210
 None
 1.40A 3kp6A-2d3yA:
undetectable
3kp6B-2d3yA:
undetectable		 3kp6A-2d3yA:
19.48
3kp6B-2d3yA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 TRP A  39
ALA A 116
VAL A  43
 None
 0.93A 3l8lA-2d3yA:
undetectable
3l8lB-2d3yA:
undetectable		 3l8lA-2d3yA:
8.73
3l8lB-2d3yA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 TRP A  39
ALA A 116
VAL A  43
 None
 0.80A 3l8lC-2d3yA:
undetectable
3l8lD-2d3yA:
undetectable		 3l8lC-2d3yA:
8.73
3l8lD-2d3yA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 HIS A  63
SER A  77
ASN A 120
 None
ACT  A 222 ( 4.2A)
None
 0.88A 3s8pB-2d3yA:
undetectable		 3s8pB-2d3yA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 10 ALA A 112
GLY A  57
LEU A  54
LEU A 158
LEU A 150
 None
ACT  A 222 ( 4.7A)
None
None
None
 1.14A 3wdmB-2d3yA:
undetectable		 3wdmB-2d3yA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 9 ALA A 112
GLY A  57
LEU A  54
LEU A 158
LEU A 150
 None
ACT  A 222 ( 4.7A)
None
None
None
 1.09A 3wdmC-2d3yA:
undetectable		 3wdmC-2d3yA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ARG A  41
ARG A  23
TRP A  39
 None
SF4  A 220 ( 4.8A)
None
 1.33A 4b7nA-2d3yA:
undetectable		 4b7nA-2d3yA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ARG A  41
ARG A  23
TRP A  39
 None
SF4  A 220 ( 4.8A)
None
 1.33A 4cpzC-2d3yA:
undetectable		 4cpzC-2d3yA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ARG A  41
ARG A  23
TRP A  39
 None
SF4  A 220 ( 4.8A)
None
 1.37A 4cpzE-2d3yA:
undetectable		 4cpzE-2d3yA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ARG A  41
ARG A  23
TRP A  39
 None
SF4  A 220 ( 4.8A)
None
 1.33A 4cpzF-2d3yA:
undetectable		 4cpzF-2d3yA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ARG A  41
ARG A  23
TRP A  39
 None
SF4  A 220 ( 4.8A)
None
 1.40A 4cpzG-2d3yA:
undetectable		 4cpzG-2d3yA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ARG A  41
ARG A  23
TRP A  39
 None
SF4  A 220 ( 4.8A)
None
 1.26A 4cpzH-2d3yA:
undetectable		 4cpzH-2d3yA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 11 PHE A  72
SER A  65
GLY A  64
GLY A  78
ALA A 175
 ACT  A 222 (-4.0A)
ACT  A 222 (-2.8A)
None
None
None
 1.17A 4l6v1-2d3yA:
undetectable
4l6v6-2d3yA:
undetectable		 4l6v1-2d3yA:
15.20
4l6v6-2d3yA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.40A 4uh0A-2d3yA:
undetectable
4uh0B-2d3yA:
undetectable		 4uh0A-2d3yA:
19.25
4uh0B-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 5 LEU A 102
ASP A 100
TYR A 105
LEU A 104
 None
None
None
DU  A 221 (-4.1A)
 1.27A 4wozF-2d3yA:
undetectable
4wozH-2d3yA:
undetectable		 4wozF-2d3yA:
20.07
4wozH-2d3yA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 12 ASP A  75
SER A  77
VAL A  43
GLY A  57
LEU A  81
 ACT  A 222 ( 4.9A)
ACT  A 222 ( 4.2A)
None
ACT  A 222 ( 4.7A)
None
 0.95A 4y8wA-2d3yA:
undetectable		 4y8wA-2d3yA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 12 ASP A  75
SER A  77
VAL A  43
GLY A  57
LEU A  81
 ACT  A 222 ( 4.9A)
ACT  A 222 ( 4.2A)
None
ACT  A 222 ( 4.7A)
None
 0.98A 4y8wB-2d3yA:
undetectable		 4y8wB-2d3yA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 12 ASP A  75
SER A  77
VAL A  43
GLY A  57
LEU A  81
 ACT  A 222 ( 4.9A)
ACT  A 222 ( 4.2A)
None
ACT  A 222 ( 4.7A)
None
 0.94A 4y8wC-2d3yA:
undetectable		 4y8wC-2d3yA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 MET A 211
VAL A 148
PHE A 206
GLU A 208
 None
 1.44A 5ad5A-2d3yA:
undetectable
5ad5B-2d3yA:
undetectable		 5ad5A-2d3yA:
19.25
5ad5B-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.40A 5ad6A-2d3yA:
undetectable
5ad6B-2d3yA:
undetectable		 5ad6A-2d3yA:
19.25
5ad6B-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 MET A 211
VAL A 148
PHE A 206
GLU A 208
 None
 1.43A 5adaA-2d3yA:
undetectable
5adaB-2d3yA:
undetectable		 5adaA-2d3yA:
19.25
5adaB-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 MET A 211
VAL A 148
PHE A 206
GLU A 208
 None
 1.46A 5adiA-2d3yA:
undetectable
5adiB-2d3yA:
undetectable		 5adiA-2d3yA:
20.99
5adiB-2d3yA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 HIS A  63
SER A  77
ASN A 120
 None
ACT  A 222 ( 4.2A)
None
 0.82A 5cprB-2d3yA:
undetectable		 5cprB-2d3yA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.45A 5fvtA-2d3yA:
undetectable
5fvtB-2d3yA:
undetectable		 5fvtA-2d3yA:
19.25
5fvtB-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.41A 5fw0A-2d3yA:
undetectable
5fw0B-2d3yA:
undetectable		 5fw0A-2d3yA:
19.25
5fw0B-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  55
LEU A 219
GLY A 106
ALA A  51
LEU A 141
 None
 1.23A 5iktB-2d3yA:
undetectable		 5iktB-2d3yA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 6 LEU A 155
THR A 110
LEU A 185
LEU A 216
 None
 0.80A 5tudD-2d3yA:
undetectable		 5tudD-2d3yA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.43A 5unsA-2d3yA:
undetectable
5unsB-2d3yA:
undetectable		 5unsA-2d3yA:
19.25
5unsB-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.43A 5untA-2d3yA:
undetectable
5untB-2d3yA:
undetectable		 5untA-2d3yA:
19.25
5untB-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.37A 5unuA-2d3yA:
undetectable
5unuB-2d3yA:
undetectable		 5unuA-2d3yA:
19.25
5unuB-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.38A 5vuiA-2d3yA:
undetectable
5vuiB-2d3yA:
undetectable		 5vuiA-2d3yA:
19.25
5vuiB-2d3yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.45A 6autA-2d3yA:
undetectable
6autB-2d3yA:
undetectable		 6autA-2d3yA:
14.36
6autB-2d3yA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2d3y URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 PHE A 206
GLU A 208
MET A 211
VAL A 148
 None
 1.42A 6auuA-2d3yA:
undetectable
6auuB-2d3yA:
undetectable		 6auuA-2d3yA:
14.36
6auuB-2d3yA:
14.36