SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d4g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB152_0 (ILEAL BILE ACID-BINDING PROTEIN)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	3 / 3	ASN A 57 HIS A 54 VAL A 103	None	0.88A	3elzB-2d4gA: undetectable	3elzB-2d4gA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NT1_A_NPSA5_1 (PROSTAGLANDIN-ENDOPE ROXIDE SYNTHASE 2)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	5 / 12	LEU A 99 LEU A 7 ALA A 59 SER A 62 LEU A 167	None	1.02A	3nt1A-2d4gA: undetectable	3nt1A-2d4gA: 16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NT1_B_NPSB4_1 (PROSTAGLANDIN-ENDOPE ROXIDE SYNTHASE 2)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	5 / 12	LEU A 99 LEU A 7 ALA A 59 SER A 62 LEU A 167	None	1.01A	3nt1B-2d4gA: undetectable	3nt1B-2d4gA: 16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	4 / 6	GLU A 97 GLN A 108 HIS A 115 ASN A 111	None	1.31A	4pfjB-2d4gA: undetectable	4pfjB-2d4gA: 17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JVZ_A_FLPA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	5 / 12	LEU A 99 LEU A 7 ALA A 59 SER A 62 LEU A 167	None	1.05A	5jvzA-2d4gA: undetectable	5jvzA-2d4gA: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JVZ_B_FLPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	5 / 12	LEU A 99 LEU A 7 ALA A 59 SER A 62 LEU A 167	None	1.04A	5jvzB-2d4gA: undetectable	5jvzB-2d4gA: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8O_B_CHDB1001_0 (GASTROTROPIN)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	5 / 12	GLN A 120 ILE A 31 LEU A 35 VAL A 6 SER A 40	None	1.33A	5l8oB-2d4gA: 0.0	5l8oB-2d4gA: 23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NKN_A_LOCA201_2 (NEUTROPHIL GELATINASE-ASSOCIATE D LIPOCALIN)	2d4g	HYPOTHETICAL PROTEIN BSU11850 (Bacillus subtilis)	3 / 3	VAL A 81 LYS A 85 MET A 69	None	0.81A	5nknA-2d4gA: undetectable	5nknA-2d4gA: 17.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ELZ_B_CHDB152_0","ILEAL BILE ACID-BINDING PROTEIN","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",3,"ASN A  57;HIS A  54;VAL A 103","None","0.88A","3elzB-2d4gA:undetectable","3elzB-2d4gA:22.22"],["3NT1_A_NPSA5_1","PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",5,"LEU A  99;LEU A   7;ALA A  59;SER A  62;LEU A 167","None","1.02A","3nt1A-2d4gA:undetectable","3nt1A-2d4gA:16.73"],["3NT1_B_NPSB4_1","PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",5,"LEU A  99;LEU A   7;ALA A  59;SER A  62;LEU A 167","None","1.01A","3nt1B-2d4gA:undetectable","3nt1B-2d4gA:16.73"],["4PFJ_B_ADNB502_2","ADENOSYLHOMOCYSTEINASE","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",4,"GLU A  97;GLN A 108;HIS A 115;ASN A 111","None","1.31A","4pfjB-2d4gA:undetectable","4pfjB-2d4gA:17.91"],["5JVZ_A_FLPA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",5,"LEU A  99;LEU A   7;ALA A  59;SER A  62;LEU A 167","None","1.05A","5jvzA-2d4gA:undetectable","5jvzA-2d4gA:16.56"],["5JVZ_B_FLPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",5,"LEU A  99;LEU A   7;ALA A  59;SER A  62;LEU A 167","None","1.04A","5jvzB-2d4gA:undetectable","5jvzB-2d4gA:16.56"],["5L8O_B_CHDB1001_0","GASTROTROPIN","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",5,"GLN A 120;ILE A  31;LEU A  35;VAL A   6;SER A  40","None","1.33A","5l8oB-2d4gA:0.0","5l8oB-2d4gA:23.89"],["5NKN_A_LOCA201_2","NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN","2d4g","HYPOTHETICAL PROTEIN BSU11850","Bacillus subtilis",3,"VAL A  81;LYS A  85;MET A  69","None","0.81A","5nknA-2d4gA:undetectable","5nknA-2d4gA:17.26"]]