SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d4n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 2d4n DU
(Mason-Pfizer
monkey
virus) 		4 / 8 THR A 154
GLY A 156
LEU A 206
ILE A 110
 None
 0.88A 3nbqB-2d4nA:
undetectable		 3nbqB-2d4nA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 2d4n DU
(Mason-Pfizer
monkey
virus) 		4 / 8 THR A 154
GLY A 156
LEU A 206
ILE A 110
 None
 0.80A 3nbqC-2d4nA:
undetectable		 3nbqC-2d4nA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 2d4n DU
(Mason-Pfizer
monkey
virus) 		4 / 7 LEU A 208
LEU A 123
PRO A 109
ILE A 110
 None
 0.90A 3s56B-2d4nA:
undetectable		 3s56B-2d4nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 2d4n DU
(Mason-Pfizer
monkey
virus) 		4 / 6 LEU A 169
MET A 137
LEU A 142
ILE A 158
 None
None
None
DUP  A 777 ( 4.5A)
 1.09A 4okxA-2d4nA:
undetectable		 4okxA-2d4nA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2d4n DU
(Mason-Pfizer
monkey
virus) 		4 / 5 LEU A 125
CYH A 126
THR A 128
GLY A 145
 None
 1.20A 6gtqA-2d4nA:
undetectable		 6gtqA-2d4nA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2d4n DU
(Mason-Pfizer
monkey
virus) 		4 / 5 LEU A 125
THR A 144
CYH A 126
GLY A 145
 None
 1.17A 6gtqA-2d4nA:
undetectable		 6gtqA-2d4nA:
22.80