SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d4w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  85
VAL A 101
TRP A 102
 None
None
MPD  A   1 ( 3.9A)
 0.89A 1av2A-2d4wA:
undetectable
1av2B-2d4wA:
undetectable		 1av2A-2d4wA:
4.98
1av2B-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 TRP A 102
ALA A  85
VAL A 101
 MPD  A   1 ( 3.9A)
None
None
 0.91A 1av2C-2d4wA:
undetectable
1av2D-2d4wA:
undetectable		 1av2C-2d4wA:
4.98
1av2D-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 GLU A 113
ILE A 110
ARG A 151
 None
 0.78A 1cd2A-2d4wA:
undetectable		 1cd2A-2d4wA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  85
VAL A 101
TRP A 102
 None
None
MPD  A   1 ( 3.9A)
 0.96A 1gmkA-2d4wA:
undetectable
1gmkB-2d4wA:
undetectable		 1gmkA-2d4wA:
4.98
1gmkB-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  85
VAL A 101
TRP A 102
 None
None
MPD  A   1 ( 3.9A)
 1.02A 1gmkC-2d4wA:
undetectable
1gmkD-2d4wA:
undetectable		 1gmkC-2d4wA:
4.98
1gmkD-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 8 VAL A 127
TYR A 123
GLY A 128
LEU A 193
 None
 0.92A 1jlbA-2d4wA:
2.9		 1jlbA-2d4wA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.81A 1jo3A-2d4wA:
undetectable		 1jo3A-2d4wA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.81A 1jo3B-2d4wA:
undetectable		 1jo3B-2d4wA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.96A 1jo4A-2d4wA:
undetectable		 1jo4A-2d4wA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.96A 1jo4B-2d4wA:
undetectable		 1jo4B-2d4wA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.88A 1nrmA-2d4wA:
undetectable		 1nrmA-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.88A 1nrmB-2d4wA:
undetectable		 1nrmB-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.88A 1nt5A-2d4wA:
undetectable		 1nt5A-2d4wA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.88A 1nt5B-2d4wA:
undetectable		 1nt5B-2d4wA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.77A 1nt6A-2d4wA:
undetectable		 1nt6A-2d4wA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  99
VAL A  87
TRP A  88
 None
 0.77A 1nt6B-2d4wA:
undetectable		 1nt6B-2d4wA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 8 VAL A 127
TYR A 123
GLY A 128
LEU A 193
 None
 0.94A 1s1xA-2d4wA:
4.2		 1s1xA-2d4wA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  85
VAL A 101
TRP A 102
 None
None
MPD  A   1 ( 3.9A)
 0.90A 1w5uA-2d4wA:
undetectable
1w5uB-2d4wA:
undetectable		 1w5uA-2d4wA:
4.98
1w5uB-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 TRP A 102
ALA A  85
VAL A 101
 MPD  A   1 ( 3.9A)
None
None
 0.88A 1w5uA-2d4wA:
undetectable
1w5uB-2d4wA:
undetectable		 1w5uA-2d4wA:
4.98
1w5uB-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 5 MET A 397
ASN A 270
THR A 265
GLN A 247
 None
 1.49A 1xmuA-2d4wA:
undetectable		 1xmuA-2d4wA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 ALA A  85
VAL A 101
TRP A 102
 None
None
MPD  A   1 ( 3.9A)
 0.93A 2izqA-2d4wA:
undetectable
2izqB-2d4wA:
undetectable		 2izqA-2d4wA:
4.98
2izqB-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 TRP A 102
ALA A  85
VAL A 101
 MPD  A   1 ( 3.9A)
None
None
 0.96A 2izqC-2d4wA:
undetectable
2izqD-2d4wA:
undetectable		 2izqC-2d4wA:
4.98
2izqD-2d4wA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 11 HIS A 228
ALA A  75
VAL A 235
GLY A 242
ILE A  78
 None
 1.20A 2uxpB-2d4wA:
undetectable		 2uxpB-2d4wA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 11 THR A 186
SER A 222
TYR A 226
ALA A 448
ALA A 249
 None
 1.49A 2xh9A-2d4wA:
undetectable		 2xh9A-2d4wA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 10 THR A 186
SER A 222
TYR A 226
ALA A 448
ALA A 249
 None
 1.47A 2xh9B-2d4wA:
0.5		 2xh9B-2d4wA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 12 ALA A 362
ALA A 349
PRO A 348
VAL A 492
GLU A 392
 None
MPD  A2001 (-3.5A)
MPD  A2001 (-4.7A)
None
None
 1.09A 3cwkA-2d4wA:
undetectable		 3cwkA-2d4wA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 12 LEU A 199
LEU A 196
THR A 166
VAL A 291
PRO A 217
 None
 1.23A 3dcjA-2d4wA:
2.9
3dcjB-2d4wA:
undetectable		 3dcjA-2d4wA:
19.23
3dcjB-2d4wA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 12 ASN A 187
VAL A 168
ALA A  99
THR A 173
ILE A 243
 None
 1.26A 3dl9B-2d4wA:
undetectable		 3dl9B-2d4wA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 TRP A 102
ALA A  85
VAL A 101
 MPD  A   1 ( 3.9A)
None
None
 0.97A 3l8lA-2d4wA:
undetectable
3l8lB-2d4wA:
undetectable		 3l8lA-2d4wA:
4.98
3l8lB-2d4wA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		3 / 3 TRP A 102
ALA A  85
VAL A 101
 MPD  A   1 ( 3.9A)
None
None
 0.94A 3l8lC-2d4wA:
undetectable
3l8lD-2d4wA:
undetectable		 3l8lC-2d4wA:
4.98
3l8lD-2d4wA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 4 ASP A 197
ASP A 195
GLY A 128
THR A 191
 None
 0.92A 3tl9B-2d4wA:
undetectable		 3tl9B-2d4wA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 12 ILE A  73
VAL A  59
ILE A  78
LEU A 169
VAL A 180
 None
 1.12A 3w68C-2d4wA:
1.7		 3w68C-2d4wA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.47A 4e3aA-2d4wA:
undetectable		 4e3aA-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.48A 4e3aB-2d4wA:
undetectable		 4e3aB-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.48A 4k8pA-2d4wA:
undetectable		 4k8pA-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.48A 4k8pB-2d4wA:
undetectable		 4k8pB-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.47A 4k8tA-2d4wA:
undetectable		 4k8tA-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.48A 4k8tB-2d4wA:
undetectable		 4k8tB-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.48A 4k93A-2d4wA:
undetectable		 4k93A-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.48A 4k93B-2d4wA:
undetectable		 4k93B-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.47A 4k9cA-2d4wA:
undetectable		 4k9cA-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.47A 4k9iA-2d4wA:
undetectable		 4k9iA-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.48A 4k9iB-2d4wA:
undetectable		 4k9iB-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.47A 4kadA-2d4wA:
undetectable		 4kadA-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.47A 4kadB-2d4wA:
undetectable		 4kadB-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 6 LEU A 216
ILE A 205
THR A 191
GLY A 137
 None
 1.04A 4l39A-2d4wA:
undetectable		 4l39A-2d4wA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.46A 4lbxA-2d4wA:
undetectable		 4lbxA-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.46A 4lbxB-2d4wA:
undetectable		 4lbxB-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		6 / 12 GLY A 245
ASN A  80
THR A 290
LEU A 288
GLU A  83
THR A 183
 None
None
None
None
MPD  A   1 (-2.7A)
None
 1.47A 4lc4B-2d4wA:
undetectable		 4lc4B-2d4wA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 7 MET A 476
GLU A 480
GLU A 482
TYR A 485
 None
 1.21A 4mj8C-2d4wA:
undetectable		 4mj8C-2d4wA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 10 LEU A 287
ASN A 398
LEU A 428
LEU A 408
VAL A 430
 None
 1.16A 4po0A-2d4wA:
undetectable		 4po0A-2d4wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 8 LEU A 428
GLY A 429
GLU A 482
MET A 476
 None
 0.86A 4rjdA-2d4wA:
undetectable
4rjdB-2d4wA:
undetectable		 4rjdA-2d4wA:
9.79
4rjdB-2d4wA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		5 / 9 GLY A 458
ALA A 255
VAL A 462
GLU A 258
ILE A 451
 None
 1.50A 5i3cA-2d4wA:
undetectable		 5i3cA-2d4wA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 6 ILE A  78
VAL A  55
VAL A 168
SER A  15
 None
 0.95A 5jwaH-2d4wA:
undetectable		 5jwaH-2d4wA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 8 VAL A 310
GLY A 352
GLN A 389
LEU A 353
 MPD  A2001 (-4.0A)
None
None
None
 0.93A 5sxqA-2d4wA:
undetectable		 5sxqA-2d4wA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 8 VAL A 310
GLY A 352
GLN A 389
LEU A 353
 MPD  A2001 (-4.0A)
None
None
None
 0.88A 5sxtA-2d4wA:
undetectable		 5sxtA-2d4wA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 8 VAL A 310
GLY A 352
GLN A 389
LEU A 353
 MPD  A2001 (-4.0A)
None
None
None
 0.89A 5sxtB-2d4wA:
undetectable		 5sxtB-2d4wA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 8 VAL A 310
GLY A 352
GLN A 389
LEU A 353
 MPD  A2001 (-4.0A)
None
None
None
 0.98A 5syjB-2d4wA:
undetectable		 5syjB-2d4wA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 2d4w GLYCEROL KINASE
(Cellulomonas
sp.) 		4 / 7 SER A 283
LEU A 304
ALA A 396
LEU A 272
 None
 1.03A 5te8A-2d4wA:
undetectable		 5te8A-2d4wA:
21.71