SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d4z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3007_1 (TRANSCRIPTIONAL REGULATOR TCAR)	2d4z	CHLORIDE CHANNEL PROTEIN (Torpedo marmorata)	5 / 9	ASN A 580 THR A 581 LEU A 583 ALA A 551 SER A 552	None	1.45A	3kp6B-2d4zA: undetectable	3kp6B-2d4zA: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B7N_A_ZMRA601_2 (NEURAMINIDASE)	2d4z	CHLORIDE CHANNEL PROTEIN (Torpedo marmorata)	3 / 3	ARG A 598 ARG A 706 TRP A 703	None	1.49A	4b7nA-2d4zA: undetectable	4b7nA-2d4zA: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_F_ZMRF1470_2 (NEURAMINIDASE)	2d4z	CHLORIDE CHANNEL PROTEIN (Torpedo marmorata)	3 / 3	ARG A 598 ARG A 706 TRP A 703	None	1.50A	4cpzF-2d4zA: undetectable	4cpzF-2d4zA: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_G_ZMRG1471_2 (NEURAMINIDASE)	2d4z	CHLORIDE CHANNEL PROTEIN (Torpedo marmorata)	3 / 3	ARG A 598 ARG A 706 TRP A 703	None	1.47A	4cpzG-2d4zA: undetectable	4cpzG-2d4zA: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	2d4z	CHLORIDE CHANNEL PROTEIN (Torpedo marmorata)	3 / 3	LEU A 738 GLY A 743 PHE A 570	None	0.55A	6exiC-2d4zA: undetectable	6exiC-2d4zA: 19.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KP6_B_SALB3007_1","TRANSCRIPTIONAL REGULATOR TCAR","2d4z","CHLORIDE CHANNEL PROTEIN","Torpedo marmorata",5,"ASN A 580;THR A 581;LEU A 583;ALA A 551;SER A 552","None","1.45A","3kp6B-2d4zA:undetectable","3kp6B-2d4zA:23.15"],["4B7N_A_ZMRA601_2","NEURAMINIDASE","2d4z","CHLORIDE CHANNEL PROTEIN","Torpedo marmorata",3,"ARG A 598;ARG A 706;TRP A 703","None","1.49A","4b7nA-2d4zA:undetectable","4b7nA-2d4zA:19.92"],["4CPZ_F_ZMRF1470_2","NEURAMINIDASE","2d4z","CHLORIDE CHANNEL PROTEIN","Torpedo marmorata",3,"ARG A 598;ARG A 706;TRP A 703","None","1.50A","4cpzF-2d4zA:undetectable","4cpzF-2d4zA:19.74"],["4CPZ_G_ZMRG1471_2","NEURAMINIDASE","2d4z","CHLORIDE CHANNEL PROTEIN","Torpedo marmorata",3,"ARG A 598;ARG A 706;TRP A 703","None","1.47A","4cpzG-2d4zA:undetectable","4cpzG-2d4zA:19.74"],["6EXI_C_ADNC502_1","ADENOSYLHOMOCYSTEINASE","2d4z","CHLORIDE CHANNEL PROTEIN","Torpedo marmorata",3,"LEU A 738;GLY A 743;PHE A 570","None","0.55A","6exiC-2d4zA:undetectable","6exiC-2d4zA:19.05"]]