SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 ASP A 153
VAL A 164
GLY A 211
GLY A 198
 None
 0.89A 1ekjE-2d5lA:
undetectable
1ekjF-2d5lA:
undetectable		 1ekjE-2d5lA:
17.20
1ekjF-2d5lA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 11 ALA A 625
LEU A 666
ALA A 663
ALA A 692
LEU A 672
 None
 1.04A 1jinA-2d5lA:
undetectable		 1jinA-2d5lA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 9 VAL A 517
TYR A 604
GLY A 601
TRP A 632
LEU A 659
 None
 1.30A 1lwfA-2d5lA:
undetectable		 1lwfA-2d5lA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 6 ASP A 490
GLY A 491
THR A 493
PRO A 494
 None
 0.84A 1n4fA-2d5lA:
undetectable		 1n4fA-2d5lA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 PHE A 689
LEU A 688
THR A 698
PRO A 700
LEU A 666
 None
 1.12A 1og5A-2d5lA:
undetectable		 1og5A-2d5lA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 PHE A 689
LEU A 688
THR A 698
PRO A 700
LEU A 666
 None
 1.14A 1og5B-2d5lA:
undetectable		 1og5B-2d5lA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 VAL A 566
TYR A 604
ASP A 645
PHE A 644
GLU A 575
 None
 1.09A 1p5zB-2d5lA:
2.4		 1p5zB-2d5lA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		3 / 3 ILE A 441
ILE A 459
THR A 455
 None
 0.52A 1rg7A-2d5lA:
undetectable		 1rg7A-2d5lA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 TYR A 518
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.37A 1x70A-2d5lA:
33.1		 1x70A-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 SER A 603
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.42A 1x70B-2d5lA:
33.5		 1x70B-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 ILE A 208
VAL A 201
HIS A 259
ALA A 222
VAL A 261
 None
 1.30A 2g72B-2d5lA:
undetectable		 2g72B-2d5lA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 ILE A 459
ILE A 352
ILE A 413
VAL A 383
LEU A 434
 None
 1.13A 2qo5A-2d5lA:
undetectable		 2qo5A-2d5lA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 205
TYR A 518
TYR A 604
VAL A 629
TYR A 639
 None
 1.12A 2rguA-2d5lA:
31.0		 2rguA-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 GLU A 636
TRP A 602
SER A 603
TYR A 604
TYR A 639
HIS A 710
 None
 1.19A 2rguA-2d5lA:
31.0		 2rguA-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		9 / 12 TYR A 518
TRP A 602
SER A 603
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.77A 2rguA-2d5lA:
31.0		 2rguA-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 11 GLU A 205
TYR A 518
TYR A 604
VAL A 629
TYR A 639
 None
 1.13A 2rguB-2d5lA:
33.1		 2rguB-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 11 GLU A 636
TRP A 602
SER A 603
TYR A 604
TYR A 639
HIS A 710
 None
 1.17A 2rguB-2d5lA:
33.1		 2rguB-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 11 GLU A 636
TYR A 518
TRP A 602
TYR A 604
TYR A 639
HIS A 710
 None
 1.32A 2rguB-2d5lA:
33.1		 2rguB-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		8 / 11 TRP A 602
SER A 603
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.62A 2rguB-2d5lA:
33.1		 2rguB-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		8 / 11 TYR A 518
TRP A 602
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.77A 2rguB-2d5lA:
33.1		 2rguB-2d5lA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 7 TYR A 721
VAL A 534
TYR A  50
ILE A 539
 None
 0.96A 2xz5B-2d5lA:
undetectable
2xz5E-2d5lA:
undetectable		 2xz5B-2d5lA:
14.80
2xz5E-2d5lA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 ILE A 539
TYR A 721
VAL A 534
TYR A  50
 None
 1.02A 2xz5A-2d5lA:
undetectable
2xz5C-2d5lA:
undetectable		 2xz5A-2d5lA:
14.80
2xz5C-2d5lA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 ILE A 539
TYR A 721
VAL A 534
TYR A  50
 None
 1.03A 2xz5C-2d5lA:
undetectable
2xz5D-2d5lA:
undetectable		 2xz5C-2d5lA:
14.80
2xz5D-2d5lA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 7 ILE A 539
TYR A 721
VAL A 534
TYR A  50
 None
 1.00A 2xz5D-2d5lA:
undetectable
2xz5E-2d5lA:
undetectable		 2xz5D-2d5lA:
14.80
2xz5E-2d5lA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		3 / 3 TYR A 643
GLU A 564
ASN A 361
 None
 0.96A 2y7hC-2d5lA:
undetectable		 2y7hC-2d5lA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 ALA A 222
LEU A 276
GLY A 320
ASP A 316
 None
 0.65A 2yfxA-2d5lA:
undetectable		 2yfxA-2d5lA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		3 / 3 SER A 290
GLU A 329
ASP A 358
 None
 0.80A 2zulA-2d5lA:
undetectable		 2zulA-2d5lA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 205
TYR A 518
TYR A 604
VAL A 629
TYR A 639
 None
 0.89A 3bjmA-2d5lA:
31.3		 3bjmA-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
HIS A 710
 None
 1.03A 3bjmA-2d5lA:
31.3		 3bjmA-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		8 / 12 TYR A 518
SER A 603
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.45A 3bjmA-2d5lA:
31.3		 3bjmA-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 205
TYR A 518
SER A 603
TYR A 639
VAL A 680
 None
 1.16A 3bjmB-2d5lA:
31.0		 3bjmB-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 205
TYR A 518
SER A 603
VAL A 629
TYR A 639
 None
 0.88A 3bjmB-2d5lA:
31.0		 3bjmB-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		7 / 12 TYR A 518
SER A 603
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.49A 3bjmB-2d5lA:
31.0		 3bjmB-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 5 LEU A 614
ASP A 665
ILE A 630
GLY A 664
 None
 0.85A 3bufA-2d5lA:
undetectable		 3bufA-2d5lA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 495
VAL A 515
GLY A 582
THR A 574
VAL A 566
 None
 1.14A 3c6gB-2d5lA:
undetectable		 3c6gB-2d5lA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		3 / 3 SER A 290
GLU A 329
ASP A 358
 None
 0.77A 3dmhA-2d5lA:
undetectable		 3dmhA-2d5lA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
HIS A 710
 None
 1.16A 3g0bA-2d5lA:
31.3		 3g0bA-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 SER A 603
TYR A 604
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.64A 3g0bA-2d5lA:
31.3		 3g0bA-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		7 / 12 TYR A 518
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.69A 3g0bA-2d5lA:
31.3		 3g0bA-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
VAL A 681
HIS A 710
 None
 1.15A 3g0bB-2d5lA:
31.1		 3g0bB-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 SER A 603
TYR A 604
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.63A 3g0bB-2d5lA:
31.1		 3g0bB-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		7 / 12 TYR A 518
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.69A 3g0bB-2d5lA:
31.1		 3g0bB-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
VAL A 681
HIS A 710
 None
 1.16A 3g0bC-2d5lA:
33.5		 3g0bC-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 SER A 603
TYR A 604
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.67A 3g0bC-2d5lA:
33.5		 3g0bC-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		7 / 12 TYR A 518
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.72A 3g0bC-2d5lA:
33.5		 3g0bC-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
VAL A 681
HIS A 710
 None
 1.14A 3g0bD-2d5lA:
32.3		 3g0bD-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		7 / 12 TYR A 518
SER A 603
TYR A 604
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.85A 3g0bD-2d5lA:
32.3		 3g0bD-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		7 / 12 TYR A 518
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.71A 3g0bD-2d5lA:
32.3		 3g0bD-2d5lA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 4 LEU A 670
PRO A 700
LEU A 666
ARG A 662
 None
 1.43A 3hcoA-2d5lA:
3.6		 3hcoA-2d5lA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_1
(O-METHYLTRANSFERASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 4 ASP A 294
SER A 347
PHE A 343
SER A 215
 None
 1.46A 3i5uA-2d5lA:
undetectable		 3i5uA-2d5lA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 TYR A 721
THR A 725
ALA A 542
THR A 500
 None
 0.82A 3jusB-2d5lA:
undetectable		 3jusB-2d5lA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 5 SER A 355
ARG A 357
ARG A 371
GLY A 370
 None
 1.27A 3k9fA-2d5lA:
undetectable
3k9fB-2d5lA:
undetectable
3k9fC-2d5lA:
3.1		 3k9fA-2d5lA:
20.75
3k9fB-2d5lA:
20.75
3k9fC-2d5lA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 289
HIS A 267
LEU A 276
GLY A 320
THR A 319
 None
 1.31A 3okxA-2d5lA:
undetectable		 3okxA-2d5lA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 289
HIS A 267
LEU A 276
GLY A 320
THR A 319
 None
 1.33A 3okxB-2d5lA:
undetectable		 3okxB-2d5lA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 7 ILE A 442
ILE A 444
VAL A  55
LEU A  57
 None
 0.67A 3r9vA-2d5lA:
undetectable
3r9vB-2d5lA:
undetectable		 3r9vA-2d5lA:
17.97
3r9vB-2d5lA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 4 GLY A 626
GLY A 606
THR A 609
LEU A 670
 None
 0.87A 3si7C-2d5lA:
undetectable
3si7D-2d5lA:
undetectable		 3si7C-2d5lA:
17.71
3si7D-2d5lA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 8 GLY A 158
SER A 155
GLY A 218
ILE A 171
LEU A 268
 None
 1.27A 3v1nA-2d5lA:
16.6		 3v1nA-2d5lA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
HIS A 710
 None
 1.01A 3w2tA-2d5lA:
32.0		 3w2tA-2d5lA:
26.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		8 / 12 TYR A 518
SER A 603
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.32A 3w2tA-2d5lA:
32.0		 3w2tA-2d5lA:
26.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
HIS A 710
 None
 1.04A 3w2tB-2d5lA:
33.3		 3w2tB-2d5lA:
26.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		8 / 12 TYR A 518
SER A 603
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.38A 3w2tB-2d5lA:
33.3		 3w2tB-2d5lA:
26.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		3 / 3 ASP A 358
GLU A 380
GLY A 379
 None
 0.61A 3w9tA-2d5lA:
undetectable		 3w9tA-2d5lA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 6 GLY A 520
LEU A 571
TYR A 643
GLU A 564
 None
 1.12A 3w9tB-2d5lA:
undetectable		 3w9tB-2d5lA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 5 ASP A 358
GLU A 380
GLY A 379
GLN A 375
 None
 1.21A 3w9tB-2d5lA:
undetectable		 3w9tB-2d5lA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 6 GLY A 520
LEU A 571
TYR A 643
GLU A 564
 None
 1.12A 3w9tE-2d5lA:
undetectable		 3w9tE-2d5lA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 6 GLY A 520
LEU A 571
TYR A 643
GLU A 564
 None
 1.14A 3w9tF-2d5lA:
undetectable		 3w9tF-2d5lA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 TRP A 602
ARG A 717
TYR A 516
HIS A 600
 None
 1.48A 3zmdA-2d5lA:
undetectable
3zmdB-2d5lA:
undetectable		 3zmdA-2d5lA:
14.12
3zmdB-2d5lA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 TYR A 721
VAL A 534
TYR A  50
ILE A 539
 None
 0.94A 4aftD-2d5lA:
undetectable
4aftE-2d5lA:
undetectable		 4aftD-2d5lA:
14.80
4aftE-2d5lA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 TYR A 721
VAL A 534
TYR A  50
ILE A 539
 None
 0.91A 4bqtC-2d5lA:
undetectable
4bqtD-2d5lA:
undetectable		 4bqtC-2d5lA:
14.80
4bqtD-2d5lA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		6 / 12 TYR A 518
SER A 603
VAL A 629
TYR A 635
VAL A 681
HIS A 710
 None
 0.40A 4ffwA-2d5lA:
31.7		 4ffwA-2d5lA:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 205
GLY A 207
TYR A 518
VAL A 629
TYR A 639
 None
 1.12A 4ffwB-2d5lA:
31.6		 4ffwB-2d5lA:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 205
TYR A 518
SER A 603
TYR A 639
VAL A 680
 None
 1.32A 4ffwB-2d5lA:
31.6		 4ffwB-2d5lA:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 205
TYR A 518
SER A 603
VAL A 629
TYR A 639
 None
 0.87A 4ffwB-2d5lA:
31.6		 4ffwB-2d5lA:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLY A 207
TYR A 518
VAL A 629
TYR A 635
TYR A 639
 None
 1.01A 4ffwB-2d5lA:
31.6		 4ffwB-2d5lA:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		7 / 12 TYR A 518
SER A 603
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.37A 4ffwB-2d5lA:
31.6		 4ffwB-2d5lA:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 VAL A 517
TYR A 518
GLY A 572
SER A 603
GLY A 606
 None
 1.08A 4mm8A-2d5lA:
undetectable		 4mm8A-2d5lA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 10 VAL A 517
TYR A 518
GLY A 572
SER A 603
GLY A 606
 None
 1.03A 4mmdA-2d5lA:
undetectable		 4mmdA-2d5lA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 VAL A 517
TYR A 518
GLY A 572
SER A 603
GLY A 606
 None
 1.08A 4mmdB-2d5lA:
undetectable		 4mmdB-2d5lA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 6 SER A 290
LEU A 289
TYR A 315
LEU A 298
 None
 0.78A 4wozA-2d5lA:
2.4
4wozB-2d5lA:
2.1		 4wozA-2d5lA:
18.52
4wozB-2d5lA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 5 TYR A 604
MET A 608
THR A 609
LEU A 612
 None
 1.07A 5x1fW-2d5lA:
undetectable		 5x1fW-2d5lA:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 GLU A 636
SER A 603
TYR A 604
TYR A 639
HIS A 710
 None
 1.05A 6b1eB-2d5lA:
31.2		 6b1eB-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		8 / 12 TYR A 518
SER A 603
TYR A 604
VAL A 629
TYR A 635
TYR A 639
VAL A 681
HIS A 710
 None
 0.36A 6b1eB-2d5lA:
31.2		 6b1eB-2d5lA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 670
GLY A 668
VAL A 583
VAL A 619
ASP A 618
 None
 1.27A 6bxlB-2d5lA:
undetectable		 6bxlB-2d5lA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE
(Porphyromonas
gingivalis) 		4 / 6 ILE A 567
GLY A 520
TYR A 643
GLU A 575
 None
 0.95A 6gqiA-2d5lA:
undetectable		 6gqiA-2d5lA:
21.21