SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 2d5u N-GLYCANASE 1
(Mus
musculus) 		4 / 7 SER A  37
LEU A 103
ILE A 110
GLY A  84
 None
 0.84A 2v0mC-2d5uA:
undetectable		 2v0mC-2d5uA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2d5u N-GLYCANASE 1
(Mus
musculus) 		5 / 12 LEU A  48
ILE A 106
GLN A 102
ILE A  47
PHE A  85
 None
 1.12A 4rp8C-2d5uA:
undetectable		 4rp8C-2d5uA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2d5u N-GLYCANASE 1
(Mus
musculus) 		4 / 4 CYH A  79
LEU A  40
LEU A  25
ALA A  36
 None
 1.13A 5hpuA-2d5uA:
undetectable
5hpuB-2d5uA:
undetectable		 5hpuA-2d5uA:
10.26
5hpuB-2d5uA:
12.90