SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 2d5v HEPATOCYTE NUCLEAR
FACTOR 6
(Rattus
norvegicus) 		4 / 8 LEU A  43
VAL A  31
ILE A  22
TYR A  20
 None
 0.95A 2weyB-2d5vA:
undetectable		 2weyB-2d5vA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2d5v HEPATOCYTE NUCLEAR
FACTOR 6
(Rattus
norvegicus) 		4 / 6 VAL A 107
THR A 105
LEU A 126
GLU A 118
 None
 0.84A 5tudD-2d5vA:
undetectable		 5tudD-2d5vA:
16.16