SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d6l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 8 PHE X  92
VAL X  46
VAL X 119
VAL X 111
None
0.95A 1iwiA-2d6lX:
undetectable
1iwiA-2d6lX:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.23A 1jffB-2d6lX:
undetectable
1jffB-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 11 LEU X  33
VAL X  46
PHE X  48
VAL X  31
THR X 145
None
1.30A 1q23F-2d6lX:
undetectable
1q23F-2d6lX:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.23A 2hxfB-2d6lX:
undetectable
2hxfB-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.23A 2hxhB-2d6lX:
undetectable
2hxhB-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.23A 2p4nB-2d6lX:
undetectable
2p4nB-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 PRO X  16
VAL X 135
GLN X   7
PHE X 146
ILE X 144
None
1.32A 2v95A-2d6lX:
undetectable
2v95A-2d6lX:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.23A 2wbeB-2d6lX:
undetectable
2wbeB-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 6 GLN X  89
PHE X  92
LEU X 100
PHE X 102
None
1.17A 3ablP-2d6lX:
undetectable
3ablW-2d6lX:
undetectable
3ablP-2d6lX:
21.43
3ablW-2d6lX:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.23A 3dcoB-2d6lX:
undetectable
3dcoB-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.23A 3edlB-2d6lX:
undetectable
3edlB-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
PHE X  44
LEU X 139
THR X  36
None
1.23A 3edlB-2d6lX:
undetectable
3edlB-2d6lX:
17.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_A_1GNA998_1
(GALECTIN-7)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
6 / 6 HIS X  60
ASN X  62
ARG X  64
ASN X  74
TRP X  81
GLU X  84
None
0.31A 3galA-2d6lX:
22.4
3galA-2d6lX:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_B_1GNB999_1
(GALECTIN-7)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
6 / 6 HIS X  60
ASN X  62
ARG X  64
ASN X  74
TRP X  81
GLU X  84
None
0.40A 3galB-2d6lX:
22.4
3galB-2d6lX:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 4 PRO X   9
THR X 145
GLY X  35
THR X  36
None
1.18A 3ib1A-2d6lX:
undetectable
3ib1A-2d6lX:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.21A 3iz0B-2d6lX:
undetectable
3iz0B-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
PHE X  44
LEU X 139
THR X  36
None
1.22A 3iz0B-2d6lX:
undetectable
3iz0B-2d6lX:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 LEU X  33
VAL X  46
PHE X  48
VAL X  31
PHE X  17
None
1.13A 3u9fB-2d6lX:
undetectable
3u9fC-2d6lX:
undetectable
3u9fB-2d6lX:
17.05
3u9fC-2d6lX:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 LEU X  33
VAL X  46
PHE X  48
VAL X  31
PHE X  17
None
1.13A 3u9fH-2d6lX:
undetectable
3u9fI-2d6lX:
undetectable
3u9fH-2d6lX:
17.05
3u9fI-2d6lX:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 11 LEU X  33
VAL X  46
PHE X  48
VAL X  31
PHE X  17
None
1.13A 3u9fN-2d6lX:
undetectable
3u9fO-2d6lX:
undetectable
3u9fN-2d6lX:
17.05
3u9fO-2d6lX:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 PHE X  17
LEU X  33
VAL X  46
PHE X  48
VAL X  31
None
1.11A 3u9fP-2d6lX:
undetectable
3u9fS-2d6lX:
undetectable
3u9fP-2d6lX:
17.05
3u9fS-2d6lX:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 SER X 136
VAL X  46
GLN X   7
PHE X 146
ILE X 144
None
1.19A 4c49A-2d6lX:
undetectable
4c49A-2d6lX:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 LEU X  25
PHE X 109
ILE X  21
ILE X 133
VAL X  46
None
1.04A 4nkvD-2d6lX:
undetectable
4nkvD-2d6lX:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.14A 5hnwB-2d6lX:
undetectable
5hnwB-2d6lX:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
PHE X  44
LEU X 139
THR X  36
None
1.19A 5hnwB-2d6lX:
undetectable
5hnwB-2d6lX:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
LEU X 139
THR X  36
PRO X  91
None
1.19A 5hnyB-2d6lX:
undetectable
5hnyB-2d6lX:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
5 / 12 VAL X 111
LEU X 141
PHE X  44
LEU X 139
THR X  36
None
1.21A 5hnyB-2d6lX:
undetectable
5hnyB-2d6lX:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 6 GLN X  89
PHE X  92
LEU X 100
PHE X 102
None
1.01A 5z86C-2d6lX:
undetectable
5z86J-2d6lX:
undetectable
5z86C-2d6lX:
21.43
5z86J-2d6lX:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 6 GLN X  89
PHE X  92
LEU X 100
PHE X 102
None
1.00A 5z86P-2d6lX:
undetectable
5z86W-2d6lX:
undetectable
5z86P-2d6lX:
21.43
5z86W-2d6lX:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 6 GLN X  89
PHE X  92
LEU X 100
PHE X 102
None
1.00A 5zcoP-2d6lX:
undetectable
5zcoW-2d6lX:
undetectable
5zcoP-2d6lX:
21.43
5zcoW-2d6lX:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 6 GLN X  89
PHE X  92
LEU X 100
PHE X 102
None
0.98A 5zcpC-2d6lX:
undetectable
5zcpJ-2d6lX:
undetectable
5zcpC-2d6lX:
21.43
5zcpJ-2d6lX:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 6 GLN X  89
PHE X  92
LEU X 100
PHE X 102
None
1.04A 5zcpP-2d6lX:
undetectable
5zcpW-2d6lX:
undetectable
5zcpP-2d6lX:
21.43
5zcpW-2d6lX:
16.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
7 / 7 HIS X  60
ASN X  62
ARG X  64
ASN X  74
TRP X  81
GLU X  84
ARG X  86
None
0.50A 6b8kA-2d6lX:
23.5
6b8kA-2d6lX:
32.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
4 / 8 HIS X  60
ASN X  62
ARG X  43
TRP X  81
None
1.00A 6b94A-2d6lX:
19.2
6b94A-2d6lX:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
7 / 8 HIS X  60
ASN X  62
ARG X  64
ASN X  74
TRP X  81
GLU X  84
ARG X  86
None
0.52A 6b94A-2d6lX:
19.2
6b94A-2d6lX:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)
2d6l LECTIN, GALACTOSE
BINDING, SOLUBLE 9

(Mus
musculus)
7 / 10 HIS X  60
ASN X  62
ARG X  64
ASN X  74
TRP X  81
GLU X  84
ARG X  86
None
0.54A 6b94A-2d6lX:
19.2
6b94B-2d6lX:
18.8
6b94A-2d6lX:
33.67
6b94B-2d6lX:
33.67