SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  83
TRP H  36
 None
 0.90A 1av2C-2d7tH:
undetectable
1av2D-2d7tH:
undetectable		 1av2C-2d7tH:
6.52
1av2D-2d7tH:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		6 / 12 TYR L  36
LEU L  96
PHE L  98
VAL H  37
ALA H  97
TRP H 106
 None
 0.78A 1h8sA-2d7tL:
21.9		 1h8sA-2d7tL:
29.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		6 / 12 TYR L  36
TYR L  94
LEU L  96
PHE L  98
VAL H  37
TRP H 106
 None
 0.90A 1h8sA-2d7tL:
21.9		 1h8sA-2d7tL:
29.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 HIS L  34
TYR L  36
TYR L  49
LEU L  89
 None
 0.43A 1i7zA-2d7tL:
20.6		 1i7zA-2d7tL:
33.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 1.06A 1lqtB-2d7tH:
undetectable		 1lqtB-2d7tH:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 1.09A 1lquB-2d7tH:
undetectable		 1lquB-2d7tH:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens;
Homo
sapiens) 		3 / 3 THR L  97
GLU H  46
ASP H  90
 None
 0.87A 1nt2A-2d7tL:
undetectable		 1nt2A-2d7tL:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 ASP H  57
HIS H  35
LEU L  96
TRP H  50
 None
 1.06A 1pk2A-2d7tH:
undetectable		 1pk2A-2d7tH:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 TYR H  33
ASP H  57
HIS H  35
LEU L  96
 None
 1.23A 1pk2A-2d7tH:
undetectable		 1pk2A-2d7tH:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 TYR L  36
HIS L  38
PRO L  44
TYR H  95
 None
 1.23A 2ombC-2d7tL:
17.6
2ombD-2d7tL:
17.5		 2ombC-2d7tL:
27.06
2ombD-2d7tL:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 THR H  98
GLY H 102
GLY H 107
GLN H   6
LEU L  96
 None
 1.18A 3eeyH-2d7tH:
undetectable		 3eeyH-2d7tH:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 THR H  98
GLY H 102
GLY H 107
GLN H   6
LEU L  96
 None
 1.17A 3eeyI-2d7tH:
undetectable		 3eeyI-2d7tH:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 THR H  98
GLY H 102
GLY H 107
GLN H   6
LEU L  96
 None
 1.19A 3eeyJ-2d7tH:
undetectable		 3eeyJ-2d7tH:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		5 / 12 GLY H  49
VAL H  79
ILE H  51
LEU L  89
TYR L  36
 None
 1.22A 3g9eA-2d7tH:
undetectable		 3g9eA-2d7tH:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 PRO H  53
TYR H  33
GLY H  31
THR H  28
 None
 1.46A 3ib0A-2d7tH:
undetectable		 3ib0A-2d7tH:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 VAL H  20
VAL H  83
TRP H  36
 None
 0.92A 3l8lA-2d7tH:
undetectable
3l8lB-2d7tH:
undetectable		 3l8lA-2d7tH:
6.52
3l8lB-2d7tH:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		3 / 3 THR L  59
ASP L  82
GLU L  39
 None
 0.64A 3qowA-2d7tL:
undetectable		 3qowA-2d7tL:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		5 / 7 GLY H  56
PRO H  53
TYR H  33
GLY H  31
THR H  28
 None
 1.34A 3tajA-2d7tH:
undetectable		 3tajA-2d7tH:
15.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WFH_B_P2EB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		5 / 12 HIS H  35
VAL H  37
TRP H  50
TRP H 106
LEU L  89
 None
 0.64A 3wfhA-2d7tH:
22.1
3wfhB-2d7tH:
15.5		 3wfhA-2d7tH:
40.39
3wfhB-2d7tH:
22.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WHX_B_XPGB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		5 / 12 HIS H  35
VAL H  37
TRP H  50
TRP H 106
LEU L  89
 None
 0.67A 3whxA-2d7tH:
22.1
3whxB-2d7tH:
15.5		 3whxA-2d7tH:
37.61
3whxB-2d7tH:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		3 / 3 GLY L  41
PRO L  40
ALA L  84
 None
 0.50A 4qn9B-2d7tL:
undetectable		 4qn9B-2d7tL:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.19A 4v2yA-2d7tH:
0.0		 4v2yA-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.17A 4v2yB-2d7tH:
undetectable		 4v2yB-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.17A 4v2zB-2d7tH:
0.0		 4v2zB-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.18A 4v30B-2d7tH:
0.0		 4v30B-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.16A 5amiA-2d7tH:
0.0		 5amiA-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.17A 5amiB-2d7tH:
undetectable		 5amiB-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.14A 5amjB-2d7tH:
0.0		 5amjB-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		3 / 3 THR L  59
ASP L  82
GLU L  39
 None
 0.62A 5fa8A-2d7tL:
undetectable		 5fa8A-2d7tL:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 THR L  74
SER L  63
THR L  72
SER L  65
 None
 1.01A 5l4eA-2d7tL:
undetectable
5l4eB-2d7tL:
undetectable
5l4eC-2d7tL:
undetectable
5l4eD-2d7tL:
undetectable
5l4eE-2d7tL:
undetectable		 5l4eA-2d7tL:
17.78
5l4eB-2d7tL:
17.78
5l4eC-2d7tL:
17.78
5l4eD-2d7tL:
17.78
5l4eE-2d7tL:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.24A 5oh1B-2d7tH:
0.0		 5oh1B-2d7tH:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.16A 5oh3A-2d7tH:
0.0		 5oh3A-2d7tH:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 2d7t ANTI
POLYHYDROXYBUTYRATE
ANTIBODY FV, HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ASN H  52
PRO H  53
TRP H  50
TYR H  60
 None
 1.21A 5oh3B-2d7tH:
0.0		 5oh3B-2d7tH:
22.76