SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 2d8n RECOVERIN
(Homo
sapiens) 		4 / 5 ASP A  74
THR A  80
LEU A  81
GLU A  85
 None
 1.31A 4a3pA-2d8nA:
undetectable		 4a3pA-2d8nA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2d8n RECOVERIN
(Homo
sapiens) 		3 / 3 TYR A 109
ARG A  71
HIS A  68
 None
 1.23A 4fubA-2d8nA:
undetectable		 4fubA-2d8nA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2d8n RECOVERIN
(Homo
sapiens) 		3 / 3 LYS A 154
LEU A 185
ARG A 151
 None
 0.84A 5yw0A-2d8nA:
undetectable		 5yw0A-2d8nA:
20.99