SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 2d90 PDZ DOMAIN
CONTAINING PROTEIN 1
(Mus
musculus) 		4 / 4 ALA A  43
VAL A  10
PHE A  21
THR A  81
 None
 1.38A 2pkkA-2d90A:
undetectable		 2pkkA-2d90A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2d90 PDZ DOMAIN
CONTAINING PROTEIN 1
(Mus
musculus) 		4 / 6 PHE A  21
THR A  81
VAL A  71
VAL A  54
 None
 1.07A 2zuiA-2d90A:
undetectable		 2zuiA-2d90A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2d90 PDZ DOMAIN
CONTAINING PROTEIN 1
(Mus
musculus) 		5 / 8 PHE A  21
TYR A  19
THR A  81
VAL A  54
LEU A  83
 None
 1.13A 2zujA-2d90A:
undetectable		 2zujA-2d90A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2d90 PDZ DOMAIN
CONTAINING PROTEIN 1
(Mus
musculus) 		5 / 7 GLY A  20
SER A  41
ALA A  46
VAL A  10
ILE A  34
 None
 1.15A 3a2qA-2d90A:
undetectable		 3a2qA-2d90A:
14.09