SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2d96 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Homo
sapiens) 		3 / 3 TYR A  49
ARG A  61
SER A  58
 None
 0.98A 4lf7I-2d96A:
undetectable
4lf7J-2d96A:
undetectable		 4lf7I-2d96A:
19.70
4lf7J-2d96A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2d96 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Homo
sapiens) 		3 / 3 TYR A  49
ARG A  61
SER A  58
 None
 0.98A 4lf8I-2d96A:
undetectable
4lf8J-2d96A:
undetectable		 4lf8I-2d96A:
19.70
4lf8J-2d96A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 2d96 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Homo
sapiens) 		5 / 10 LEU A  36
LEU A  77
ALA A  76
LEU A  70
LEU A  40
 None
 1.07A 4p65A-2d96A:
undetectable
4p65B-2d96A:
undetectable
4p65F-2d96A:
undetectable
4p65H-2d96A:
undetectable		 4p65A-2d96A:
9.17
4p65B-2d96A:
15.84
4p65F-2d96A:
15.84
4p65H-2d96A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 2d96 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Homo
sapiens) 		5 / 11 LEU A  36
LEU A  77
ALA A  76
LEU A  40
LEU A  70
 None
 1.03A 4p65C-2d96A:
undetectable
4p65D-2d96A:
undetectable
4p65J-2d96A:
undetectable
4p65L-2d96A:
undetectable		 4p65C-2d96A:
9.17
4p65D-2d96A:
15.84
4p65J-2d96A:
15.84
4p65L-2d96A:
15.84