SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 2d9c SIGNAL-REGULATORY
PROTEIN BETA-1
(Homo
sapiens) 		4 / 6 GLY A 112
TYR A  94
ALA A 113
TYR A  95
 None
 0.85A 4ae1A-2d9cA:
4.0		 4ae1A-2d9cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2d9c SIGNAL-REGULATORY
PROTEIN BETA-1
(Homo
sapiens) 		4 / 8 SER A  82
SER A  84
SER A  25
THR A  27
 None
 0.76A 4ikjA-2d9cA:
undetectable
4ikjB-2d9cA:
3.0		 4ikjA-2d9cA:
21.92
4ikjB-2d9cA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 2d9c SIGNAL-REGULATORY
PROTEIN BETA-1
(Homo
sapiens) 		4 / 8 SER A  25
THR A  27
SER A  82
SER A  84
 None
 0.92A 4ikkA-2d9cA:
2.9
4ikkB-2d9cA:
3.1		 4ikkA-2d9cA:
21.92
4ikkB-2d9cA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 2d9c SIGNAL-REGULATORY
PROTEIN BETA-1
(Homo
sapiens) 		4 / 8 SER A  82
SER A  84
SER A  25
THR A  27
 None
 0.89A 4iklA-2d9cA:
undetectable
4iklB-2d9cA:
2.9		 4iklA-2d9cA:
21.92
4iklB-2d9cA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2d9c SIGNAL-REGULATORY
PROTEIN BETA-1
(Homo
sapiens) 		3 / 3 LYS A 101
LEU A   9
ILE A  41
 None
 0.74A 5kc0A-2d9cA:
undetectable		 5kc0A-2d9cA:
22.11