SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 2d9f FK506-BINDING
PROTEIN 8 VARIANT
(Homo
sapiens) 		4 / 6 LEU A 118
VAL A 116
VAL A  69
ASP A  74
 None
 1.14A 1dz4A-2d9fA:
undetectable		 1dz4A-2d9fA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2d9f FK506-BINDING
PROTEIN 8 VARIANT
(Homo
sapiens) 		4 / 6 LEU A 118
VAL A 116
VAL A  69
ASP A  74
 None
 1.16A 1dz4B-2d9fA:
undetectable		 1dz4B-2d9fA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2d9f FK506-BINDING
PROTEIN 8 VARIANT
(Homo
sapiens) 		4 / 6 LEU A 118
VAL A 116
VAL A  69
ASP A  74
 None
 1.05A 2zawA-2d9fA:
undetectable		 2zawA-2d9fA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2d9f FK506-BINDING
PROTEIN 8 VARIANT
(Homo
sapiens) 		4 / 7 THR A 120
VAL A  39
THR A  41
VAL A  61
 None
 0.49A 3em0B-2d9fA:
undetectable		 3em0B-2d9fA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 2d9f FK506-BINDING
PROTEIN 8 VARIANT
(Homo
sapiens) 		4 / 7 LEU A  73
VAL A  88
VAL A  42
LEU A  11
 None
 0.87A 3rgfA-2d9fA:
undetectable		 3rgfA-2d9fA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2d9f FK506-BINDING
PROTEIN 8 VARIANT
(Homo
sapiens) 		4 / 6 LEU A 118
VAL A 116
VAL A  69
ASP A  74
 None
 1.13A 4g3rB-2d9fA:
undetectable		 4g3rB-2d9fA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 2d9f FK506-BINDING
PROTEIN 8 VARIANT
(Homo
sapiens) 		4 / 6 LEU A 118
VAL A 116
VAL A  69
ASP A  74
 None
 1.11A 4kkyX-2d9fA:
undetectable		 4kkyX-2d9fA:
15.75