SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IWK_A_CUA1599_0 (NITROUS OXIDE REDUCTASE)	2d9m	ZINC FINGER CCCH-TYPE DOMAIN CONTAINING PROTEIN 7A (Homo sapiens)	3 / 3	CYH A 915 CYH A 921 HIS A 925	ZN A1085 (-2.3A) ZN A1085 (-2.3A) ZN A1085 (-3.5A)	0.80A	2iwkA-2d9mA: undetectable	2iwkA-2d9mA: 8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IWK_B_CUB1599_0 (NITROUS OXIDE REDUCTASE)	2d9m	ZINC FINGER CCCH-TYPE DOMAIN CONTAINING PROTEIN 7A (Homo sapiens)	3 / 3	CYH A 915 CYH A 921 HIS A 925	ZN A1085 (-2.3A) ZN A1085 (-2.3A) ZN A1085 (-3.5A)	0.80A	2iwkB-2d9mA: undetectable	2iwkB-2d9mA: 8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_C_SAMC530_1 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	2d9m	ZINC FINGER CCCH-TYPE DOMAIN CONTAINING PROTEIN 7A (Homo sapiens)	3 / 3	TYR A 893 GLU A 932 ASN A 927	None	0.95A	2y7hC-2d9mA: undetectable	2y7hC-2d9mA: 8.64