SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2d9o DNAJ (HSP40)
HOMOLOG, SUBFAMILY
C, MEMBER 17
(Homo
sapiens) 		4 / 5 LEU A 237
TYR A 189
LEU A 197
ARG A 196
 None
 1.44A 4em2A-2d9oA:
undetectable		 4em2A-2d9oA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2d9o DNAJ (HSP40)
HOMOLOG, SUBFAMILY
C, MEMBER 17
(Homo
sapiens) 		4 / 6 VAL A 193
LEU A 194
ARG A 196
LEU A 237
 None
 0.96A 4o1zA-2d9oA:
undetectable		 4o1zA-2d9oA:
11.15