SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2d9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 12 LEU B 171
LEU B 170
ARG B 167
ILE B 178
GLY B 177
 None
 1.23A 1g50B-2d9qB:
undetectable		 1g50B-2d9qB:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 11 LEU B 171
LEU B 170
ARG B 167
ILE B 178
GLY B 177
 None
 1.23A 1g50C-2d9qB:
undetectable		 1g50C-2d9qB:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 8 LEU B  80
ILE B  24
ILE B  25
LYS B  26
 None
 0.86A 1sbrA-2d9qB:
undetectable		 1sbrA-2d9qB:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 12 LEU B 171
LEU B 170
ARG B 167
ILE B 178
GLY B 177
 None
 1.23A 2j7xA-2d9qB:
undetectable		 2j7xA-2d9qB:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 5 LEU B 245
VAL B 202
LEU B 112
MET B 208
 None
 0.99A 2oiqA-2d9qB:
undetectable		 2oiqA-2d9qB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 6 MET B 110
MET B 199
MET B 176
LEU B 117
 None
 1.36A 2oz7A-2d9qB:
undetectable		 2oz7A-2d9qB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 12 LEU B 171
LEU B 170
ARG B 167
ILE B 178
GLY B 177
 None
 1.20A 4j26A-2d9qB:
undetectable		 4j26A-2d9qB:
21.31