SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2daq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FL5_F_RBFF204_1 (IMMUNOGLOBULIN IGG1 LAMBDA LIGHT CHAIN IMMUNOGLOBULIN IGG1 HEAVY CHAIN)	2daq	WHSC1L1 PROTEIN, ISOFORM LONG (Homo sapiens)	4 / 8	TYR A 59 GLU A 94 PHE A 52 VAL A 17	None	1.14A	2fl5E-2daqA: undetectable 2fl5F-2daqA: undetectable	2fl5E-2daqA: 20.10 2fl5F-2daqA: 21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HZN_G_ACTG225_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2daq	WHSC1L1 PROTEIN, ISOFORM LONG (Homo sapiens)	3 / 3	PRO A 36 LEU A 37 GLN A 40	None	0.68A	3hznG-2daqA: undetectable 3hznH-2daqA: undetectable	3hznG-2daqA: 19.91 3hznH-2daqA: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	2daq	WHSC1L1 PROTEIN, ISOFORM LONG (Homo sapiens)	4 / 4	ILE A 29 GLN A 13 VAL A 15 PHE A 49	None	1.10A	3ieoA-2daqA: 0.0	3ieoA-2daqA: 16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZJI_A_PQNA844_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	2daq	WHSC1L1 PROTEIN, ISOFORM LONG (Homo sapiens)	5 / 10	PHE A 88 GLY A 55 ILE A 14 ALA A 95 LEU A 92	None	1.10A	5zjiA-2daqA: undetectable 5zjiJ-2daqA: undetectable	5zjiA-2daqA: 19.49 5zjiJ-2daqA: 13.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2FL5_F_RBFF204_1","IMMUNOGLOBULIN IGG1 LAMBDA LIGHT CHAIN;IMMUNOGLOBULIN IGG1 HEAVY CHAIN","2daq","WHSC1L1 PROTEIN, ISOFORM LONG","Homo sapiens",4,"TYR A  59;GLU A  94;PHE A  52;VAL A  17","None","1.14A","2fl5E-2daqA:undetectable;2fl5F-2daqA:undetectable","2fl5E-2daqA:20.10;2fl5F-2daqA:21.00"],["3HZN_G_ACTG225_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2daq","WHSC1L1 PROTEIN, ISOFORM LONG","Homo sapiens",3,"PRO A  36;LEU A  37;GLN A  40","None","0.68A","3hznG-2daqA:undetectable;3hznH-2daqA:undetectable","3hznG-2daqA:19.91;3hznH-2daqA:19.91"],["3IEO_A_AMJA300_0","CARBONIC ANHYDRASE 2","2daq","WHSC1L1 PROTEIN, ISOFORM LONG","Homo sapiens",4,"ILE A  29;GLN A  13;VAL A  15;PHE A  49","None","1.10A","3ieoA-2daqA:0.0","3ieoA-2daqA:16.54"],["5ZJI_A_PQNA844_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;PHOTOSYSTEM I REACTION CENTER SUBUNIT IX","2daq","WHSC1L1 PROTEIN, ISOFORM LONG","Homo sapiens",5,"PHE A  88;GLY A  55;ILE A  14;ALA A  95;LEU A  92","None","1.10A","5zjiA-2daqA:undetectable;5zjiJ-2daqA:undetectable","5zjiA-2daqA:19.49;5zjiJ-2daqA:13.76"]]