SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dat'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 2dat POSSIBLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		3 / 3 PRO A  44
GLU A  54
TYR A  53
 None
 0.80A 2zmbA-2datA:
undetectable		 2zmbA-2datA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2dat POSSIBLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		3 / 3 LYS A  16
LYS A  13
PRO A  12
 None
 1.11A 4dv1L-2datA:
undetectable		 4dv1L-2datA:
18.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2dat POSSIBLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		4 / 7 LEU A  43
ALA A  91
ASN A  95
ILE A 101
 None
 0.76A 4y03A-2datA:
16.9		 4y03A-2datA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2dat POSSIBLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		4 / 7 LEU A  43
TYR A  52
ALA A  91
ILE A 101
 None
 0.85A 4y03A-2datA:
16.9		 4y03A-2datA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 2dat POSSIBLE GLOBAL
TRANSCRIPTION
ACTIVATOR SNF2L2
(Homo
sapiens) 		4 / 5 LEU A  43
ALA A  91
ASN A  95
ILE A 101
 None
 0.87A 4y03B-2datA:
16.9		 4y03B-2datA:
36.43